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Table 2 Response and adverse of neoadjuvant chemotherapy among patients with locally advanced oral cavity cancer

From: Tracking the dropout patients of neoadjuvant chemotherapy with locally advanced oral cavity cancer

 

Undergoing surgery

(N = 148)

Without surgery

(N = 23)

Χ2 value

P - value

Response a

  

0.401

0.859

 PR

81

14

  

 SD

60

8

  

 PD

7

1

  

Adverse events b

 WBC decreased

  

0.254

0.614

  Grade 0/1

137

20

  

  Grade 2/3

11

3

  

 Vomiting

  

9.082

0.003

  Grade 0/1

143

18

  

  Grade 2/3

5

5

  
  1. a The response definitions were classified according to the Response Evaluation Criteria in Solid Tumors version 1.1
  2. b The adverse events were graded according to National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0