Fig. 4

MiR-203a-3p inhibited the Src/PKC/GSK-3β-mediated re-expression of E-cadherin. (A) Expression of E-cadherin, Snail, p-EGFR, p-PKC and p-GSK-3β in LoVo-P cells transfected with the exogenous miR-203a-3p mimic. (B) Expression of E-cadherin, Snail, p-EGFR, p-PKC and p-GSK-3β in LoVo-P cells pretreated with GF109203X. (C) Invaded LoVo-P cells after pretreatment with PKC inhibitor GF109203X and labelled with purple crystal. The data represent the average of three independent experiments. **P < 0.01