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Table 2 Determinants of late access or no access to sarcoma specialized diagnosis within Netsarc+ from 2011 to 2014 (source: IGéAS cohort, RRePS – ResOs – NETSARC databases)

From: Determinants of the access to remote specialised services provided by national sarcoma reference centres

  

Univariate (N = 18,264)

Multivariate (N = 18,264)

Variables

late or no access / early access

OR

IC 95%

p-value

OR

IC 95%

p-value

Individual and clinical variables

Sex

<.0001

  

0.0048

  Male

3562/5656

1

  

1

  

  Female

3918/5128

1.21

[1.14;1.28]

 

1.09

[1.02;1.16]

 

Age

<.0001

  

0.0249

   > =75

1622/2711

1

  

1

  

   [18–25[

261/373

1.17

[0.98;1.38]

 

0.98

[0.82;1.18]

 

   [25–50[

1959/2536

1.29

[1.18;1.40]

 

1.12

[1.03;1.23]

 

   [50–75[

3638/5164

1.17

[1.09;1.26]

 

1.10

[1.02;1.19]

 

Year of diagnosis

0.0018

  

0.0061

  2011

1601/2315

1

  

1

  

  2012

1706/2501

0.98

[0.90;1.07]

 

0.95

[0.87;1.04]

 

  2013

1949/3017

0.93

[0.85;1.01]

 

0.9

[0.82;0.98]

 

  2014

2224/2951

1.09

[1.00;1.18]

 

1.03

[0.95;1.13]

 

Type of tumour

<.0001

  

< 0.0001

  Soft tissue

4666/7594

1

  

1

  

  Bone

474/578

1.33

[1.17;1.51]

 

1.10

[0.96;1.26]

 

  Viscera – GIST

917/1520

0.98

[0.89;1.07]

 

1.11

[0.99;1.26]

 

  Viscera - No GIST

1423/1092

2.12

[1.94;2.31]

 

1.96

[1.78;2.15]

 

Depth of tumour

0,0007

   

  Superficial and deep

394/650

1

     

  Superficial

1526/2376

1.06

[0.92;1.22]

    

  Deep

4865/6873

1.16

[1.02;1.33]

    

  Missing

695/885

1.29

[1.10;1.52]

    

Size of tumour

<.0001

  

< 0.0001

   > =200

475/873

1

  

1

  

   [50–200[

3304/5008

1.21

[1.07;1.36]

 

1.15

[1.02;1.31]

 

   [0–50[

2236/3294

1.24

[1.10;1.41]

 

1.30

[1.14;1.48]

 

  Missing

1465/1609

1.67

[1.46;1.91]

 

1.51

[1.31;1.74]

 

Histotype category

<.0001

   

  GIST

983/1621

1

     

  Sarcoma

4657/6179

1.24

[1.13;1.35]

    

  Tumour of intermediate malignancy

1840/2984

1.01

[0.92;1.12]

    

Grade

<.0001

  

< 0.0001

  1

749/1201

1

  

1

  

  2

2312/3784

0.98

[0.88;1.08]

 

0.89

[0.80;0.99]

 

  3

1266/1887

1.07

[0.95;1.20]

 

1.02

[0.91;1.15]

 

  Not applicable

1236/876

2.26

[1.99;2.56]

 

1.83

[1.61;2.10]

 

 Missing

1917/3036

1.01

[0.90;1.12]

 

0.93

[0.82;1.06]

 

Geographical variables

Region

<.0001

  

< 0.0001

  Auvergne-Rhône-Alpes

1013/1319

1

  

1

  

  Nouvelle-Aquitaine

564/1527

0.48

[0.42;0.54]

 

0.46

[0.40;0.52]

 

  Pays-de-la-Loire

327/709

0.60

[0.51;0.70]

 

0.60

[0.51;0.71]

 

  Centre-Val de Loire

233/470

0.64

[0.54;0.77]

 

0.64

[0.54;0.77]

 

  Provence-Alpes-Côte-d’Azur

656/1241

0.68

[0.60;0.78]

 

0.69

[0.61;0.79]

 

  Bretagne

339/659

0.67

[0.57;0.78]

 

0.70

[0.59;0.82]

 

  Corse

46/76

0.78

[0.54;1.14]

 

0.72

[0.49;1.07]

 

  Occitanie

672/1131

0.77

[0.68;0.87]

 

0.78

[0.69;0.89]

 

  Bourgogne-Franche-Comté

333/538

0.80

[0.68;0.94]

 

0.83

[0.70;0.97]

 

  Grand-Est

732/838

1.13

[1.00;1.29]

 

1.18

[1.04;1.35]

 

  Hauts-de-France

737/744

1.29

[1.13;1.47]

 

1.31

[1.14;1.50]

 

  Normandie

301/287

1.36

[1.13;1.63]

 

1.43

[1.18;1.72]

 

  Ile-de-France

1527/1245

1.59

[1.42;1.78]

 

1.77

[1.57;2.00]

 

GeoClasH classification of municipalities

<.0001

   

  Wealthy Metropolitan Areas

1824/2071

1

     

  Precarious Population Districts

3837/5748

0.75

[0.70;0.81]

    

  Residential Outskirts

913/1394

0.74

[0.67;0.82]

    

  Agricultural and Industrial Plains

582/968

0.68

[0.60;0.77]

    

  Rural Margins

324/603

0.61

[0.52;0.70]

    

Travel time to the closest reference centre for sarcoma diagnosis in minutes, quintiles)

<.0001

  

0.0073

   < = 21

1581/2119

1

  

1

  

  ] 21; 47.5]

1548/2082

0.99

[0.90;1.09]

 

1.05

[0.95;1.16]

 

  ] 47.5; 73.5]

1484/2187

0.90

[0.82;0.99]

 

1.10

[0.99;1.21]

 

  ] 73.5; 97.5]

1491/2125

0.94

[0.85;1.03]

 

1.18

[1.06;1.31]

 

   > 97.5

1376/2271

0.81

[0.74;0.89]

 

1.18

[1.06;1.31]

 

European Deprivation Index (quintiles)

< 0.0001

   

   < = − 1.3 (least deprived)

1478/2188

1

     

  ]-1.3; 1.8]

1386/2227

0.92

[0.83;1.01]

    

  ]1.8; 5.6]

1438/2248

0.94

[0.86;1.04]

    

  ]5.6; 9.2]

1501/2218

1.00

[0.91;1.09]

    

   > 9.2 (most deprived)

1677/1903

1.30

[1.18;1.43]

    

Population density (number of inhabitants/km2, quintiles)

< 0.0001

   

   < = 94.0926

1364/2304

1

     

  ] 94.0926; 306.127]

1399/2226

0.68

[0.62;0.74]

    

  ] 306.127; 1034.61]

1462/2184

0.72

[0.65;0.79]

    

  ] 1034.61; 3693.94]

1547/2104

0.77

[0.70;0.84]

    

   > 3693.94

1708/1966

0.84

[0.77;0.92]

    

APL index (spatial accessibility to general practitioners, quintiles)

< 0.0001

   

   < = 49.1 (lowest accessibility)

1528/2094

1

     

  ] 49.1; 64]

1707/1973

1.18

[1.08;1.30]

    

  ] 64; 78.4]

1408/2142

0.90

[0.82;0.99]

    

  ] 78.4; 90.7]

1403/2345

0.82

[0.74;0.90]

    

   > 90.7 (highest accessibility)

1434/2230

0.88

[0.80;0.96]