Skip to main content

Table 3 A summary of studies of the risk of cancer in tuberculosis (TB) patients compared with the general population

From: Cancer risk in tuberculosis patients in a high endemic area

  Type of TB infection Type of study Sample Size Incidence of cancer in TB patients Hazard ratio
or relative risk
Extrapulmonary
cancer type
PMID
Kuo et al.
2013
Latent Retrospective population-based study 530 7.91% All cancers:
2.07, 95% CI, 1.90-2.26
Nonpulmonary cancer:
1.71, 95% CI: 1.54-1.90
Head and neck, Digestive tract, Skin, Bladder, Hematological malignancies 23,652,313
Simonsen et al. 2014 Active Cohort study 15,024 11.6% All cancers:
1.52, 95% CI 1.45-1.59; Extrapulmonary cancer: 1.29, 95% CI: 1.22-1.36
Malignant pleural mesothelioma, Hodgkin’s lymphoma, ovarian, non-Hodgkin’s malignant lymphoma 25,216,835
Su et al. 2016 Latent Retrospective
population-based study
11,522 8.46% All cancers:
2.29, 95% CI: 1.26-4.17
Nonpulmonary cancer:
NA
Multiple myeloma, kidney, bladder, hepatobiliary, gastrointestinal 26,825,880
Everatt et al. 2017 Active Retrospective cohort study 21,986 7.2% All cancers:
1.76, 95% CI: 1.67-1.85;
Nonpulmonary cancer:
1.41, 95% CI: 1.33-1.50
Mouth and pharynx, esophagus, stomach, larynx, cervix uteri, leukemia, hematological cancers, “other” cancers 28,572,839
Chen et al.,
2020
Mixed Case-control study 32,539 cases and 12,916 controls NA All cancers:
1.68, 95% CI: 1.43-1.97;
Nonpulmonary cancer:
1.72, 95% CI: 1.46-2.02
Non-Hodgkin’s lymphoma, cervical cancer, esophageal cancer, “other” cancer, ovarian cancer, head and neck cancer, breast cancer This study
  1. NA not available