Table 3 Associations of IDO-expressing melanoma cell coverage and intensity with clinicopathological parameters
Variables | IDO expression in melanoma cells | IDO intensity in melanoma cells | ||||
|---|---|---|---|---|---|---|
IDO-negative tumors n (%) | IDO-positive tumors n (%) | p-value | Weak n (%) | Moderate or strong n (%) | p-value | |
Growth pattern | 0.050 | 1.000 | ||||
Nodular | 11 (52) | 10 (48) | 5 (50) | 5 (50) | ||
Other | 17 (81) | 4 (19) | 2 (50) | 2 (50) | ||
Presence of mitoses | 0.047 | 0.299 | ||||
Yes | 18 (58) | 13 (42) | 6 (46) | 7 (54) | ||
No | 10 (91) | 1 (9) | 1 (100) | 0 (0) | ||
Lymph node capsule rupture | 0.429 | 0.014 | ||||
Yes | 5 (56) | 4 (44) | 0 (0) | 4 (100) | ||
No | 5 (39) | 8 (62) | 6 (75) | 2 (25) | ||
Overall recurrence | 0.014 | 0.352 | ||||
Yes | 16 (44) | 20 (56) | 11 (55) | 9 (45) | ||
No | 19 (76) | 6 (24) | 2 (33) | 4 (67) | ||
Locoregional recurrence | 0.009 | 0.785 | ||||
Yes | 12 (40) | 18 (60) | 9 (50) | 9 (50) | ||
No | 24 (73) | 9 (27) | 4 (44) | 5 (56) | ||
Distal recurrence | 0.040 | 0.472 | ||||
Yes | 16 (46) | 19 (54) | 10 (53) | 9 (47) | ||
No | 20 (71) | 8 (29) | 3 (38) | 5 (63) |