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Fig. 3 | BMC Cancer

Fig. 3

From: Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer

Fig. 3

Apoptosis in therapy sensitive and resistant variants Apoptosis in therapy sensitive and resistant SKBR3 cell variants was detected by a Caspase-Glo 3/7 Assay. a Fold change in Caspase 3/7 activity in the therapy sensitive SKBR3 cell line following Gef or Lap treatment for 48 h compared to the vehicle controls. b Fold change in caspase 3/7 activity in the therapy resistant cell lines following treatment compared to non-treated cells. N = 3 ± SEM, * = p ≤ 0.05, *** = p ≤ 0.005

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BMC Cancer

ISSN: 1471-2407

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