Fig. 2

The immune states, fraction of infiltrating immune cells and chemosensitivity in the immune subgroups. a The top five modules of the immune subgroups are indicated by the heatmap. The distributions of signature scores within the immune subtypes (rows) are shown, and the dashed line indicates the median. b Correlation of DNA damage (rows) with immune subtype. c mRNA expression (median normalized expression levels) for 75 IM genes by immune subtype. d Values of key immune characteristics by immune subtype. e Infiltration of immune cells by immune subgroup. f TMB and immunophenoscore (IPS) by immune subgroup. g Chemosensitivity by immune subgroup. h Kaplan-Meier plot showing that patients who underwent chemotherapy and patients who did not undergo chemotherapy had significantly different prognoses in the PD-L1-high and PD-L1-low subgroups. i Crosstalk factor expression (median normalized expression levels) by immune subtype. *P < 0.05; **P < 0.01