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Table 2 Univariate and multivariate analyses for overall survival and leukemia-free survival in 216 patients with primary MDS

From: Elevated mature monocytes in bone marrow accompanied with a higher IPSS-R score predicts a poor prognosis in myelodysplastic syndromes

Variables

Univariate analysis for OS

P-value

Multivariate analysis for OS

P-value

Univariate analysis for LFS

P-value

Multivariate analysis for LFS

P-value

Age ≥ 60 (years)

< 0.0001

< 0.0001

0.438

–

Gender (male)

0.002

0.047

0.101

–

HB < 10 g/dl

0.003

0.080

0.554

–

NE < 0.8 × 109/L

0.005

0.039

0.003

0.120

PLT < 100 × 109/L

0.237

–

0.100

–

Monocyte < 0.1 × 109/L

0.012

–

–

–

BM blast > 5%

< 0.0001

< 0.0001

< 0.0001

0.001

IPSS-R, cytogenetic risk group

< 0.0001

0.011

0.115

–

IPSS-R, risk category

< 0.0001

–

0.001

–

PMMBM≤6% vs PMMBM> 6%

0.026

< 0.0001

0.058

0.736

  1. Abbreviations: HB hemoglobin, NE neutrophil, PLT platelet, BM bone marrow, IPSS-R Revised International Prognostic Scoring System, PMMBM the percentage of mature monocyte in bone marrow