Skip to main content

Table 1 Characteristics of all patients

From: Efficacy and acquired resistance of EGFR-TKI combined with chemotherapy as first-line treatment for Chinese patients with advanced non-small cell lung cancer in a real-world setting

Characteristic

T + C (n = 50)

T (n = 67)

p

Age (years)

  

0.294

 Median (range)

59(36–81)

61(40–84)

 

Sex

  

0.506

 Male

24(48.00%)

28(38.27%)

 

 Female

26(52.00%)

39(61.73%)

 

Histology

  

1.000

 Adenocarcinoma

50(100.00%)

67(100.00%)

 

ECOG PS

  

0.835

 0–1

49(98.00%)

66(98.77%)

 

 2

1(2.00%)

1(1.23%)

 

Smoking history

  

0.986

 Nerve

35(70.00%)

47(72.84%)

 

 Former

15(30.00%)

20(27.16%)

 

EGFR mutation

  

0.321

 Exon 19 deletion

26(52.00%)

41(55.56%)

 

 L858R

21(42.00%)

23(38.27%)

 

 Others

3(8.00%)

3(6.17%)

 

Brain metastasis

  

0.345

 Yes

9(18.00%)

17(23.46%)

 

 No

41(82.00%)

50(76.54%)

 

Stage

  

0.713

 IIIb/IIIc

3(6.00%)

3(3.70%)

 

 IV

47(94.00%)

64(96.30%)

 

Cardiovascular

   

 Hypertension

15(30.00%)

21(31.34%)

0.877

 Coronary heart disease

0(0.00%)

1(1.23%)

0.388

 Cerebrovascular disease

0(0.00%)

2(2.99%)

0.220

Metabolic

   

 Diabetes

6(12.00%)

6(8.96%)

0.593

 Hyperlipidemia

2(4.00%)

1(1.23%)

0.398

 Hyperuricemia

0(0.00%)

1(1.23%)

0.388