Fig. 2

Principal component analysis (PCA) shows that differential gene expression distinguishes serous borderline tumors (SBTs) from high-grade serous ovarian cancers (HGSOCs) and stage II from stage III HGSOC samples. a PCA of expression at 11 genes differentially expressed between SBTs (n = 4) and HGSOCs (n = 7). Principal components 1 and 2 (PC1,2) are labeled with the percent variability they explain in the data. The areas enclosed by the ellipses represent the “within 80% confidence interval” under a bivariate t-distribution. b PCA of expression at 17 genes differentially expressed between stage II (HGSOC-2, n = 3) and stage III (HGSOC-3, n = 4) HGSOC samples