Table 1 The assessment criteria of RP and ARE in this research
Grade | Radiation Therapy Oncology Group grading for ARE | Common Terminology Criteria for Adverse Events (CTCAE) v5.0 for RP |
|---|---|---|
0 | None | None |
1 | Mild dysphagia or odynophagia may require topical anesthetic or non-narcotic analgesics/may require soft diet | Asymptomatic; clinical or diagnostic observations only; intervention not indicated |
2 | Moderate dysphagia or odynophagia may require narcotic analgesics/may require puree or liquid diet | Symptomatic; medical intervention indicated; limiting instrumental ADL |
3 | Severe dysphagia or odynophagia with dehydration or weight loss > 15% from pretreatment baseline/requiring N-G feeding tube, iv. fluids or hyperalimentation | Severe symptoms; limiting self-care ADL; oxygen indicated |
4 | Complete obstruction, ulceration, perforation, fistula | Life-threatening respiratory compromise; urgent intervention indicated (e.g., tracheotomy or intubation) |
5 | / | Death |