Fig. 4From: The effects of secondary iron overload and iron chelation on a radiation-induced acute myeloid leukemia mouse modelProposed pro-mutagenic and pro-death influences of iron burden on the rate of RI-AML. The dose-response curve of iron burden with the pro-mutagenesis (dotted line) and pro-death (solid line) responses of HSCs. The RI-AML rate (dashed line) is the combined effect of the pro-mutagenesis and pro-death responses at a given iron doseBack to article page