Table 2 Summary of surgical characteristics of patients with and without NACT
Variable | All (n = 269) | NACT (%) (n = 46) | Non-NACT (%) (n = 223) | p value |
|---|---|---|---|---|
Laterality, no. of patient | Â | Â | Â | 0.365 |
 Unilateral | 260 (96.7) | 46 (100.0) | 214 (96.0) |  |
 Bilateral | 9 (3.3) | 0 (0.0) | 9 (4.0) |  |
Location, no. of breast | Â | Â | Â | 0.872 |
 Right | 146 (52.5) | 25 (54.3) | 121 (52.2) |  |
 Left | 132 (47.5) | 21 (45.7) | 111 (47.8) |  |
Type of mastectomy | Â | Â | Â | 0.226 |
 Skin-sparing | 181 (67.3) | 27 (58.7) | 154 (69.1) |  |
 Nipple-sparing | 88 (32.7) | 19 (41.3) | 69 (30.9) |  |
Sentinel lymph node biopsy | 230 (85.5) | 26 (56.5) | 204 (91.5) | < 0.001* |
Positive SLNB | 47 (17.5) | 7 (15.2) | 40 (17.9) | 0.832 |
Axillary lymph node dissection | 92 (34.2) | 33 (71.7) | 59 (26.5) | < 0.001* |
Breast margin positive | 3 (1.1) | 2 (4.3) | 1 (0.4) | 0.077 |
Nipple core positive | 3 (1.1) | 2 (4.3) | 1 (0.4) | 0.077 |
Type of Immediate reconstruction | Â | Â | Â | 0.408 |
 Implant-based reconstruction | 163 (60.6) | 25 (54.3) | 138 (61.9) |  |
 Autologous reconstruction | 106 (39.4) | 21 (45.7) | 85 (38.1) |  |
Type of implant-based reconstruction | Â | Â | Â | 0.001* |
 Direct to implant | 130 (79.8) | 13 (52.0) | 117 (84.8) |  |
 Tissue expander and implant | 33 (20.2) | 12 (48.0) | 21 (15.2) |  |
Type of autologous reconstruction | Â | Â | Â | 0.869 |
 Muscle-sparing free TRAM | 5 (4.7) | 0 (0.0) | 5 (5.9) |  |
 DIEP | 90 (84.9) | 19 (90.5) | 71 (83.5) |  |
 PAP | 11 (10.4) | 2 (9.5) | 9 (10.6) |  |
Specimen size (gm) | 380 ± 200 | 422 ± 216 | 372 ± 196 | 0.133 |
Flap size (gm) | 441 ± 186 | 387 ± 147 | 454 ± 192 | 0.136 |
Implant size (ml) | 300 ± 90 | 292 ± 77 | 302 ± 92 | 0.691 |
Hospital stay ± SD, day | 9.8 ± 8.1 | 9.8 ± 4.1 | 9.8 ± 8.8 | 0.990 |
Aesthetic revision surgery | 57 (21.2) | 7 (15.2) | 50 (22.4) | 0.326 |