Table 1 Patient characteristics at initial diagnosis for the total population and stratified by year of diagnosis before or after 2012

 Mean (±SD)

62 (±7.6)

61.4 (±7.2)

61.7 (±7.8)

 Median (IQR)

63 (57–67)

63 (57–63)

62 (56–67)

Age at diagnosis (years)

0.86

n (%)

  ≤ 65

 496 (62.9)

289 (64.1)

207 (64.7)

  > 65

275 (34.9)

162 (35.9)

113 (35.3)

  < 50

59 (7.5)

–

–

 50–59

219 (27.7)

–

–

 60–69

374 (47.3)

–

–

 70–80

119 (15.0)

–

–

 Unrecorded

17 (2.2)

–

–

Year of Diagnosis

n (%)

457 (58.0)

331 (42.0)

–

  < 2009

107 (13.5)

–

–

 2009–2011

261 (33.0)

–

–

 2012–2014

296 (37.4)

–

–

 2015–2018

124 (15.7)

–

–

Ethnicity

n (%)

0.04

 Caucasian

472 (59.7)

319 (74.2)

152 (63.6)

 Black African

107 (13.5)

59 (13.7)

48 (20.1)

 Black Caribbean

69 (8.6)

40 (9.3)

29 (12.1)

 Asian

22 (2.8)

12 (2.8)

10 (4.2)

 Unrecorded

119 (15.1)

–

–

PSA level

(ng/mL)

0.001

 Mean (±SD)

6.6 (± 3.4)

6.4 (±3.3)

6.9 (±3.5)

 Median (IQR)

6 (4.4–8.0)

6.0 (4.0–8.7)

6.29 (4.7–8.2)

PSA level (ng/mL)

n (%)

0.09

 0–5

273 (34.6)

173 (40.8)

100 (34.0)

 5 .1–10

350 (44.4)

193 (45.5)

157 (53.4)

 10.1–15

74 (9.4)

48 (11.3)

26 (8.8)

 15.1–20

21 (2.7)

10 (2.4)

11 (3.7)

 Unrecorded

70 (8.9)

–

–

T Stage (at DRE)

n (%)

 Benign

331 (42.0)

–

–

 T2

176 (22.3)

–

–

Number having a diagnostic MRI

n (%)

0.001

 MRI at diagnosis

235 (29.8)

64 (14.0)

171 (51.7)

 Unrecorded

553 (70.2)

393 (86.0)

160 (48.3)

Diagnostic MRI T Stage

n = 235

–

n (%)

 T0

24 (10.2)

–

–

 T2

135 (57.4)

–

–

 Unrecorded

76 (32.3)

–

–

Method of diagnostic biopsy

n (%)

0.12

 TP

254 (32.2)

141 (33.6)

113 (39.2)

 TRUS

422 (53.6)

263 (62.6)

159 (55.2)

 Other^a

32 (4.1)

16 (3.8)

16 (5.6)

 Unrecorded

80 (10.2)

–

–

Gleason Score

n (%)

0.75

  ≤ 3 + 3

595 (75.5)

357 (81.9)

238 (81.0)

 3 + 4

135 (17.1)

79 (18.1)

56 (19.1)

 Unrecorded

58 (7.4)

–

–

Number of cores taken

 Mean (±SD)

21.0 (±10.7)

–

–

 Median (IQR)

15 (12–32)

–

–

n (%)

0.08

  < 12

37 (4.7)

19 (5.6)

18 (6.8)

 12–14

266 (33.8)

141 (41.3)

125 (47.0)

 15–24

80 (10.2)

49 (14.4))

31 (11.7)

  > 25

224 (28.4)

132 (38.4)

92 (34.6

 Unrecorded

181 (23.0)

–

–

 Mean (±SD)

2.3 (±2.1)

–

–

 Median (IQR)

2 (1–3)

–

–

Number of positive cores

n (%)

0.02

 1

288 (36.6)

178 (52.4)

110 (40.6)

 2

129 (16.4)

64 (18.8)

65 (22.9)

 3

76 (9.6)

64 (12.4)

34 (12.6)

  > 3

118 (15.0)

56 (16.5)

62 (22.9)

 Unrecorded

177 (22.5)

–

–