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Table 1 The clinical characteristics of the patients that did RT and did not do RT

From: Subdivision of de-novo metastatic nasopharyngeal carcinoma based on tumor burden and pretreatment EBV DNA for therapeutic guidance of locoregional radiotherapy

Characteristic

Total

Non-LRRT

LRRT

P value

N (%)

N (%)

N (%)

 

Age (years)

 ≤ 47

246 (49.4)

87 (46.5%)

159 (51.1%)

0.355

 > 47

252 (50.6)

100 (53.5%)

152 (48.9%)

 

Gender

 Male

414 (83.1)

155 (82.9%)

259 (83.3%)

1.000

 Female

84 (16.9)

32 (17.1%)

52 (16.7%)

 

Smoking

 No smoking

278 (55.8)

109 (58.3%)

169 (54.3%)

0.403

 Smoking

220 (44.2)

78 (41.7%)

142 (45.7%)

 

Family history

 No

447 (89.8)

170 (90.9%)

277 (89.1%)

0.545

 Yes

51 (10.2)

17 (9.1%)

34 (10.9%)

 

T stage

 T1-T2

83 (16.7)

29 (15.5%)

54 (17.4%)

0.621

 T3-T4

415 (83.3)

158 (84.5%)

257 (82.6%)

 

N stage

 N0-N1

103 (20.7)

30 (16.0%)

73 (23.5%)

0.052

 N2-N3

395 (79.3)

157 (84.0%)

238 (76.5%)

 

No. of metastatic organs

 1

375 (75.3)

116 (62.0%)

259 (83.3%)

< 0.001

 > 1

123 (24.7)

71 (38.0%)

52 (16.7%)

 

No. of metastatic lesions

 ≤ 5

338 (67.9)

97 (51.9%)

241 (77.5%)

< 0.001

 > 5

160 (32.1)

90 (48.1%)

70 (22.5%)

 

EBV-DNA (Copies/ml)

 ≤ 25,000

214 (43.0)

59 (31.6%)

155 (49.8%)

< 0.001

 > 25,000

284 (57.0)

128 (68.4%)

156 (50.2%)

 

Chemotherapy regimens

 TPF

128 (25.7)

40 (21.4%)

88 (28.3%)

0.001

 TP

121 (24.3)

36 (19.3%)

85 (27.3%)

 

 PF

129 (25.9)

58 (31.0%)

71 (22.8%)

 

 GP

27 (5.4)

18 (9.6%)

9 (2.9%)

 

 Others

93 (18.7)

35 (18.7%)

58 (18.6%)