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Fig. 6 | BMC Cancer

Fig. 6

From: Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells

Fig. 6

Expression profile changes in engineered hTNFα tumor cells. a In melanoma cells A375hTNFa, mRNA of inflammatory cytokine IL6 is extensively overexpressed; (b) carcinoma cells HT29hTNFa are stimulated to overexpress TNFα apoptosis-inducing ligand TRAIL mRNA. Expression of pluripotency and stemness markers OCT4, SOX2, NESTIN and marker of cancer stem cells CD133 are not changed significantly; reverse transcriptase quantitative PCR, triplicates ± SEMs

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BMC Cancer

ISSN: 1471-2407

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