Fig. 3

LINC_00355 silencing suppressed the migration and invasion in GC cells. After HGC-27 and MKN45 cells were transfected with si-LINC_00355–1 and − 2 for 24 h, cell migration was detected by wound-healing assay (a); cell invasion was measured by Transwell assay (b); Relatively matrix metalloproteinase (MMP) 9, MMP2, and N-cadherin protein levels were measured by western blot analysis (c). All values were expressed as mean ± standard deviation. n = 3. *P < 0.05 compared with si-NC group. GC, gastric cancer; NC, negative control