Fig. 2
Development of the orthotopic PC-9 lung tumor model. PC-9 Luc+ cells were injected into the tail vein of NSG mice and (a & b) tumor growth was assessed by bioluminescence on days 7, 14, 20, 27, 35 and 43 after tumor cell injection. a Results show the evolution of the bioluminescence intensity over time and are expressed in cpm/cm2 for the thoracic area (mean ± SEM, n = 5). b Pictures show representative bioluminescence results of one PC-9 NSCLC Luc+-bearing mouse. c On day 43 after tumor cell injection, lungs from a PC-9 tumor-bearing mouse were collected and used for H&E staining. Pictures show representative results