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Table 2 Univariate and multivariate COX analysis for survival analysis of TCGA CN-AML patients

From: High HSPA8 expression predicts adverse outcomes of acute myeloid leukemia

Parameter Univariate analysis Multivariate analysis
HR 95%CI P HR 95%CI P
Age 1.026 1.008–1.044 0.003 1.031 1.011–1.051 0.002
Gender 1.052 0.609–1.817 0.765    
Bone marrow blasts 0.996 0.983–1.009 0.507    
WBC counting 0.995 0.988–1.002 0.137 0.998 0.990–1.006 0.566
Hemoglobin 0.999 0.826–1.208 0.957    
Platelet counting 1.004 0.999–1.009 0.040 1.005 0.998–1.011 0.157
FLT3 mutation 2.6 1.461–4.631 0.001 1.881 0.920–3.848 0.084
KRAS mutant 1.232 0.381–3.980 0.728    
CEBPA mutant 0.624 0.248–1.572 0.317    
TET2 mutant 0.8 0.317–2.018 0.636    
TP53 mutant 1.938 0.264–14.248 0.516    
NRAS mutant 0.24 0.033–1.742 0.158 0.282 0.036–2.234 0.231
IDH1 mutant 0.519 0.185–1.451 0.211    
IDH2 mutant 1.047 0.506–2.166 0.900    
RUNX1 mutant 2.22 1.089–4.524 0.028 2.233 0.969–5.145 0.059
NPM1 mutant 1.08 0.623–1.868 0.785    
HSPA8 2.042 1.068–3.907 0.031 2.408 1.080–5.368 0.032