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Table 2 GO analysis of 24 hub genes

From: Bioinformatics analysis of mRNA and miRNA microarray to identify the key miRNA-mRNA pairs in cisplatin-resistant ovarian cancer

Category

ID

Description

Count

P-value

Molecular function

GO:0005515

Protein binding

21

< 0.001

GO:0005524

ATP binding

6

0.039

GO:0003725

Double-stranded RNA binding

4

< 0.001

GO:0004298

Threonine-type endopeptidase activity

3

< 0.001

GO:0003727

Single-stranded RNA binding

3

0.001

Cellular component

GO:0005829

Cytosol

19

< 0.001

GO:0005737

Cytoplasm

17

< 0.001

GO:0005634

Nucleus

14

0.007

GO:0005654

Nucleoplasm

10

0.005

GO:0000502

Proteasome complex

6

< 0.001

Biological process

GO:0009615

Response to virus

10

< 0.001

GO:0060337

Type I interferon signaling pathway

9

< 0.001

GO:0051436

Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

9

< 0.001

GO:0051437

Positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

9

< 0.001

GO:0031145

Anaphase-promoting complex-dependent catabolic process

9

< 0.001