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Fig. 4 | BMC Cancer

Fig. 4

From: COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells

Fig. 4

The effect of COXIBs, 2,5-DMC, PKF118–310 and topotecan on apoptosis (panel a) and cell cycle distribution (panel b) in A-172, T98G and U-138 MG cell lines. The concentration of compounds used in this assay provided at least 70% of cell viability. Mean values ± SD from two independent experiments are shown. In panel a, asterisk inside and hashes above bars indicate statistically significant changes for either early or late and total apoptosis, respectively, p < 0.05. In panel b, asterisk inside bars indicate statistically significant changes, p < 0.05

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