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Table 3 Univariate and multivariate analyses for DFS in training cohort

From: Prognostic value of inflammation-based indices in patients with resected hepatocellular carcinoma

Variable Univariate analysis Multivariate analysis
p Hazard ratio 95%confidence interval p Hazard ratio 95%confidence interval
Age (years)(≥60 versus < 60) 0.355 0.819 0.537–1.250    
Gender (female versus male) 0.437 0.783 0.422–1.452    
HBsAg (yes versus no) 0.345 1.306 0.750–2.274    
Cirrhosis (yes versus no) 0.405 1.154 0.823–1.618    
Tumor size (> 5 versus ≤5) < 0.001 2.332 1.650–3.296   
Tumor number (multiple versus single) < 0.001 2.198 1.551–3.114 0.014 1.599 1.101–2.323
AFP(≥400 versus < 400) 0.044 1.452 1.010–2.087 0.042 1.471 1.014–2.135
Vascular invasion (yes versus no) < 0.001 2.095 1.485–2.955   
Child-Pugh grade (B versus A) 0.067 1.746 0.963–3.166    
BCLC Stage(B + C versus 0 + A) < 0.001 2.893 1.932–4.332 0.001 2.078 1.333–3.238
Differentiation (poor versus well/moderate) 0.112 1.568 0.900–2.730    
PT (≥13.7 versus < 13.7) 0.326 0.841 0.595–1.188    
ALT (≥ 34 versus < 34) 0.100 1.347 0.944–1.920    
TB (≥12.5 versus < 12.5) 0.889 1.026 0.719–1.463    
GGT (≥49 versus < 49) < 0.001 2.084 1.431–3.036 0.006 1.714 1.163–2.526
ALB (≥39.0 versus < 39.0) 0.437 0.871 0.616–1.233    
MPV (≥11.2 versus < 11.2) 0.228 1.257 0.867–1.822    
co NLR-PDW < 0.001 2.292 1.737–3.024 < 0.001 2.370 1.781–3.152
  1. Notes: AFP alpha fetoprotein, BCLC Barcelona Clinic Liver Cancer, PT prothrombin time, ALT Alanine transaminase, TB total bilirubin, GGT gamma-glutamyl transpeptidase, ALB albumin, MPV mean platelet volume, coNLR-PDW combination of NLR and PDW, DFS disease free survival