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Table 3 Univariate and multivariate analyses for DFS in training cohort

From: Prognostic value of inflammation-based indices in patients with resected hepatocellular carcinoma

Variable

Univariate analysis

Multivariate analysis

p

Hazard ratio

95%confidence interval

p

Hazard ratio

95%confidence interval

Age (years)(≥60 versus < 60)

0.355

0.819

0.537–1.250

   

Gender (female versus male)

0.437

0.783

0.422–1.452

   

HBsAg (yes versus no)

0.345

1.306

0.750–2.274

   

Cirrhosis (yes versus no)

0.405

1.154

0.823–1.618

   

Tumor size (> 5 versus ≤5)

< 0.001

2.332

1.650–3.296

  

Tumor number (multiple versus single)

< 0.001

2.198

1.551–3.114

0.014

1.599

1.101–2.323

AFP(≥400 versus < 400)

0.044

1.452

1.010–2.087

0.042

1.471

1.014–2.135

Vascular invasion (yes versus no)

< 0.001

2.095

1.485–2.955

  

Child-Pugh grade (B versus A)

0.067

1.746

0.963–3.166

   

BCLC Stage(B + C versus 0 + A)

< 0.001

2.893

1.932–4.332

0.001

2.078

1.333–3.238

Differentiation (poor versus well/moderate)

0.112

1.568

0.900–2.730

   

PT (≥13.7 versus < 13.7)

0.326

0.841

0.595–1.188

   

ALT (≥ 34 versus < 34)

0.100

1.347

0.944–1.920

   

TB (≥12.5 versus < 12.5)

0.889

1.026

0.719–1.463

   

GGT (≥49 versus < 49)

< 0.001

2.084

1.431–3.036

0.006

1.714

1.163–2.526

ALB (≥39.0 versus < 39.0)

0.437

0.871

0.616–1.233

   

MPV (≥11.2 versus < 11.2)

0.228

1.257

0.867–1.822

   

co NLR-PDW

< 0.001

2.292

1.737–3.024

< 0.001

2.370

1.781–3.152

  1. Notes: AFP alpha fetoprotein, BCLC Barcelona Clinic Liver Cancer, PT prothrombin time, ALT Alanine transaminase, TB total bilirubin, GGT gamma-glutamyl transpeptidase, ALB albumin, MPV mean platelet volume, coNLR-PDW combination of NLR and PDW, DFS disease free survival