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Table 2 Univariate and multivariate analyses for OS in training cohort

From: Prognostic value of inflammation-based indices in patients with resected hepatocellular carcinoma

Variable

Univariate analysis

Multivariate analysis

p

Hazard ratio

95%confidence interval

p

Hazard ratio

95%confidence interval

Age (years)(≥60 versus < 60)

0.066

0.380

0.136–1.065

   

Gender (female versus male)

0.783

0.865

0.308–2.431

   

HBsAg (yes versus no)

0.184

2.621

0.633–10.850

   

Cirrhosis (yes versus no)

0.652

1.153

0.621–2.140

   

Tumor size(> 5 versus ≤5)

0.002

2.664

1.424–4.983

  

Tumor number (multiple versus single)

0.087

1.726

0.924–3.223

   

AFP(≥400 versus < 400)

0.007

2.310

1.253–4.258

0.001

2.782

1.496–5.173

Vascular invasion (yes versus no)

0.007

2.327

1.261–4.293

  

Child-Pugh grade (B versus A)

0.351

0.389

0.053–2.828

   

BCLC Stage(B + C versus 0 + A)

0.010

2.543

1.248–5.181

  

Differentiation (poor versus well/moderate)

0.285

1.666

0.653–4.247

   

PT (≥13.7 versus < 13.7)

0.094

0.578

0.304–1.099

   

ALT (≥ 34 versus < 34)

0.037

2.082

1.046–4.146

  

TB (≥12.5 versus < 12.5)

0.230

0.688

0.373–1.268

   

GGT (≥49 versus < 49)

0.001

3.825

1.697–8.626

0.001

3.852

1.690–8.782

ALB (≥39.0 versus < 39.0)

0.201

1.548

0.792–3.028

   

MPV (≥11.2 versus < 11.2)

0.424

1.300

0.684–2.470

   

co NLR-PDW

< 0.001

3.342

1.960–5.699

< 0.001

3.721

2.150–6.440

  1. Notes: AFP alpha fetoprotein, BCLC Barcelona Clinic Liver Cancer, PT prothrombin time, ALT Alanine transaminase, TB total bilirubin, GGT gamma-glutamyl transpeptidase, ALB albumin, MPV mean platelet volume, coNLR-PDW combination of NLR and PDW, OS overall survival