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Table 3 Univariate and multivariate analysis to identify potential predictor in predicting regional lymph node metastasis

From: Development and validation of multiparametric MRI-based nomogram for predicting occult metastasis risk in early tongue squamous cell carcinoma

 

Univariate analysis

Multivariate analysis

OR (95% CI)

P Value

OR (95% CI)

P Value

Age

≤ 60

Reference

0.433 (0.137–1.376)

0.209

–

–

>  60

Gender

Male

Reference

0.957 (0.390–2.351)

1.000

–

–

Female

Tumor size

T1

Reference

59.933 (7.797–460.704)

0.000

Reference

15.175 (1.436–160.329)

0.024

T2

Tumor location

Anterior/

Middle

Reference

5.395 (2.259–12.888)

0.003

Reference

6.311 (1.514–26.304)

0.011

Posterior

rTTT*

Minimal rTTT

Reference

31.067 (10.407–111.518)

0.000

Reference

11.528 (2.483–53.530)

0.002

Significant rTTT

PLD

> 5 mm

Reference

29.000 (6.486–129.668)

0.000

Reference

11.976 (1.981–72.413)

0.007

≤ 5 mm

SLD

>  4 mm

Reference

3.780 (1.417–10.088)

0.006

–

–

≤ 4 mm

Cell-differentiation

Well

Reference

1.241 (0.552–2.792)

0.681

–

–

Moderate/

Poor

  1. Abbreviations: OR = odds ratio, CI = confidence interval, PLD = Paralingual Distance, SLD = Sublingual Distance
  2. * rTTT (radiologic tumor thickness threshold) was categorized into two groups: “minimal” and “significant” rTTT, depending on how many MRI-assessed tumor thicknesses exceed their cutoff values. Minimal rTTT was defined as only one orientation of MRI thickness (either aTT, cTT or sTT) found to be greater than its defined cutoff value or no MRI thicknesses exceeding their cutoff values, whereas significant rTTT was defined as at least two orientations of MRI thickness (either aTT, cTT or sTT) exceeding their cutoff values
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BMC Cancer

ISSN: 1471-2407

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