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Table 1 Patient characteristics

From: Development and validation of multiparametric MRI-based nomogram for predicting occult metastasis risk in early tongue squamous cell carcinoma

Patient characteristics

N (%)

Primary Cohort

(N = 120)

Validation Cohort

(N = 41)

Age at diagnosis [year]

 • ≤ 60

87 (72.5)

24 (58.5)

 • >  60

33 (27.5)

17 (41.5)

Gender

 • Male

71 (59.2)

23 (56.1)

 • Female

49 (40.8)

18 (43.9)

Tumor size

 • T1

59 (49.2)

21 (51.2)

 • T2

61 (50.8)

20 (48.8)

Tumor Location

 • Anterior/Middle

76 (63.3)

24 (58.5)

 • Posterior

44 (36.7)

17 (41.5)

MRI parameters [mm]

 1.MRI-assessed tumor thickness in 3D

  • Tumor thickness in axial view (aTT)

    ≤ 8.5 mm

81 (67.5)

25 (61)

    > 8.5 mm

39 (32.5)

16 (39)

  • Tumor thickness in coronal view (cTT)

    ≤ 11 mm

69 (57.5)

11 (26.8)

    > 11 mm

51 (42.5)

30 (73.2)

  • Tumor thickness in sagittal view (sTT)

    ≤ 12 mm

75 (62.5)

19 (46.3)

    > 12 mm

45 (37.5)

22 (53.7)

 2. Paralingual distance (PLD)

   ≤ 5 mm

60 (50)

24 (58.5)

   >  5 mm

60 (50)

17 (41.5)

 3. Sublingual distance (SLD)

   ≤ 4 mm

73 (60.8)

28 (68.3)

   >  4 mm

47 (39.2)

13 (31.7)

Pathological node status

 • pN0

88 (73.3)

29 (70.7)

 • pN+

32 (26.7)

12 (29.3)

Postoperative pathological thickness*

 • ≤ 5 mm

23 (19.2)

4 (9.8)

 • >  5 mm to ≤10 mm

83 (69.2)

31 (75.6)

 • > 10 mm

14 (11.7)

6 (14.6)

Cell-differentiation

 • Well

61 (50.8)

26 (63.4)

 • Moderate/Poor

59 (49.2)

15 (36.6)

  1. * This study included only flat tumors in which the mucosal plane was at the same level as the tumor. Then the pathologic depth of invasion and pathological tumor thickness could be measured identically (pDOI = pTT)