Fig. 6

Translation efficiency (TE) in normal and tumor samples. a TE of oncogenes in normal and tumor samples. “***” represented p-value < 0.001. b TE of TSG in normal and tumor samples. c Regression coefficients of “Y ~ X1 + X2 + ...Xn”. Y is the TE fold change of tumor samples to normal samples. The variables were scaled to the same range of − 1 to 1. The variables included number of optimal synonymous mutations, number of non-optimal synonymous mutations, gene length, conservation level (dN), gene expression, and GC content