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Table 2 Univariate and multivariate logistic regression analysis for the associated risk factors for developing liver metastasis in patients diagnosed with cervical cancer

From: Incidence, clinical risk and prognostic factors for liver metastasis in patients with cervical cancer: a population-based retrospective study

Subject characteristics Univariate analysis Multivariate analysis
OR (95% CI) P-value OR (95% CI) P-value
Age in years
 18–40 Ref 1.00 Ref 1.00
 41–64 2.331 (1.736–3.129) < 0.001 1.071 (0.772–1.486) 0.681
  ≥ 65 3.603 (2.623–4.949) < 0.001 1.105 (0.770–1.586) 0.587
Race
 White Ref 1.00 Ref 1.00
 Black 1.608 (1.263–2.047) < 0.001 1.469 (1.118–1.932) 0.006
 Others 1.098 (0.802–1.504) 0.559 1.088 (0.757–1.565) 0.648
 Unknown NA NA NA NA
Insurance
 Insured Ref 1.00 Ref 1.00
 Uninsured 1.525 (1.099–2.115) 0.012 1.632 (1.124–2.368) 0.010
 Unknown NA NA NA NA
T stage
 T1 Ref 1.00 Ref 1.00
 T2 3.085 (2.185–4.356) < 0.001 1.216 (0.827–1.789) 0.320
 T3 8.717 (6.421–11.835) < 0.001 1.703 (1.179–2.460) 0.005
 T4 16.020 (11.107–23.107) < 0.001 2.699 (1.741–4.185) < 0.001
 Unknown NA NA NA NA
N stage
 N0 Ref 1.00 Ref 1.00
 N1 5.156 (4.125–6.443) < 0.001 1.650 (1.274–2.138) < 0.001
 Unknown NA NA NA NA
Grade
 I Ref 1.00 Ref 1.00
 II 4.866 (1.760–13.451) 0.002 3.127 (1.094–8.935) 0.033
 III 17.498 (6.486–47.205) < 0.001 5.509 (1.960–15.417) 0.001
 IV 35.940 (12.541–103.001) < 0.001 7.639 (2.503–23.311) < 0.001
 Unknown NA NA NA NA
Histology
 SCC Ref 1.00 Ref 1.00
 AC 1.334 (1.046–1.702) 0.002 2.052 (1.544–2.727) < 0.001
 Others 3.476 (2.774–4.355) < 0.001 2.262 (1.716–2.982) < 0.001
Tumor size
  ≤ 2 cm Ref 1.00 Ref 1.00
  > 2, ≤4 cm 3.552 (1.821–6.928) < 0.001 1.564 (0.764–3.202) 0.221
  > 4 cm 10.075 (5.603–18.116) < 0.001 1.601 (0.834–3.071) 0.157
 Unknown NA NA NA NA
Surgery primary site
 No Ref 1.00 Ref 1.00
 yes 0.090 (0.066–0.122) < 0.001 0.341 (0.235–0.493) < 0.001
 Unknown NA NA NA NA
Lung Met
 No Ref 1.00 Ref 1.00
 Yes 29.471 (23.892–36.353) < 0.001 7.272 (5.687–9.299) < 0.001
 Unknown NA NA NA NA
Bone Met
 No Ref 1.00 Ref 1.00
 Yes 25.272 (19.976–31.971) < 0.001 4.875 (3.679–6.460) < 0.001
 Unknown NA NA NA NA
Brain Met
 No Ref 1.00 Ref 1.00
 Yes 14.272 (8.357–24.373) < 0.001 4.655 (1.770–12.245) 0.002
 Unknown NA NA NA NA
  1. Notes: NA, not available; Met, Metastasis