Table 2 Univariate and multivariate logistic regression analysis for the associated risk factors for developing liver metastasis in patients diagnosed with cervical cancer
Subject characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |
Age in years | ||||
 18–40 | Ref | 1.00 | Ref | 1.00 |
 41–64 | 2.331 (1.736–3.129) | < 0.001 | 1.071 (0.772–1.486) | 0.681 |
  ≥ 65 | 3.603 (2.623–4.949) | < 0.001 | 1.105 (0.770–1.586) | 0.587 |
Race | ||||
 White | Ref | 1.00 | Ref | 1.00 |
 Black | 1.608 (1.263–2.047) | < 0.001 | 1.469 (1.118–1.932) | 0.006 |
 Others | 1.098 (0.802–1.504) | 0.559 | 1.088 (0.757–1.565) | 0.648 |
 Unknown | NA | NA | NA | NA |
Insurance | ||||
 Insured | Ref | 1.00 | Ref | 1.00 |
 Uninsured | 1.525 (1.099–2.115) | 0.012 | 1.632 (1.124–2.368) | 0.010 |
 Unknown | NA | NA | NA | NA |
T stage | ||||
 T1 | Ref | 1.00 | Ref | 1.00 |
 T2 | 3.085 (2.185–4.356) | < 0.001 | 1.216 (0.827–1.789) | 0.320 |
 T3 | 8.717 (6.421–11.835) | < 0.001 | 1.703 (1.179–2.460) | 0.005 |
 T4 | 16.020 (11.107–23.107) | < 0.001 | 2.699 (1.741–4.185) | < 0.001 |
 Unknown | NA | NA | NA | NA |
N stage | ||||
 N0 | Ref | 1.00 | Ref | 1.00 |
 N1 | 5.156 (4.125–6.443) | < 0.001 | 1.650 (1.274–2.138) | < 0.001 |
 Unknown | NA | NA | NA | NA |
Grade | ||||
 I | Ref | 1.00 | Ref | 1.00 |
 II | 4.866 (1.760–13.451) | 0.002 | 3.127 (1.094–8.935) | 0.033 |
 III | 17.498 (6.486–47.205) | < 0.001 | 5.509 (1.960–15.417) | 0.001 |
 IV | 35.940 (12.541–103.001) | < 0.001 | 7.639 (2.503–23.311) | < 0.001 |
 Unknown | NA | NA | NA | NA |
Histology | ||||
 SCC | Ref | 1.00 | Ref | 1.00 |
 AC | 1.334 (1.046–1.702) | 0.002 | 2.052 (1.544–2.727) | < 0.001 |
 Others | 3.476 (2.774–4.355) | < 0.001 | 2.262 (1.716–2.982) | < 0.001 |
Tumor size | ||||
  ≤ 2 cm | Ref | 1.00 | Ref | 1.00 |
  > 2, ≤4 cm | 3.552 (1.821–6.928) | < 0.001 | 1.564 (0.764–3.202) | 0.221 |
  > 4 cm | 10.075 (5.603–18.116) | < 0.001 | 1.601 (0.834–3.071) | 0.157 |
 Unknown | NA | NA | NA | NA |
Surgery primary site | ||||
 No | Ref | 1.00 | Ref | 1.00 |
 yes | 0.090 (0.066–0.122) | < 0.001 | 0.341 (0.235–0.493) | < 0.001 |
 Unknown | NA | NA | NA | NA |
Lung Met | ||||
 No | Ref | 1.00 | Ref | 1.00 |
 Yes | 29.471 (23.892–36.353) | < 0.001 | 7.272 (5.687–9.299) | < 0.001 |
 Unknown | NA | NA | NA | NA |
Bone Met | ||||
 No | Ref | 1.00 | Ref | 1.00 |
 Yes | 25.272 (19.976–31.971) | < 0.001 | 4.875 (3.679–6.460) | < 0.001 |
 Unknown | NA | NA | NA | NA |
Brain Met | ||||
 No | Ref | 1.00 | Ref | 1.00 |
 Yes | 14.272 (8.357–24.373) | < 0.001 | 4.655 (1.770–12.245) | 0.002 |
 Unknown | NA | NA | NA | NA |