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Table 3 Comparison of characteristics, efficacy and safety in patients undergoing ultrasound-guided lung biopsy between 16-gauge and 18-gauge core biopsy needle when number of pleural surface crossed was 2

From: Propensity-score-matching analysis to compare efficacy and safety between 16-gauge and 18-gauge needle in ultrasound-guided biopsy for peripheral pulmonary lesions

Variable Overall cohort Propensity-score matched cohort
16-gauge (n = 147) 18-gauge (n = 647) P value 16-gauge (n = 145) 18-gauge (n = 145) P value
Age (years) 57.8 ± 14.2 60.6 ± 12.4 0.016 58.3 ± 13.6 58.1 ± 13.3 0.889
Gender
 Male/female 94/53 436/211 0.424 94/51 96/49 0.805
Patient position
 Supine/prone/lateral 52/69/26 232/313/102 0.846 51/69/25 48/74/23 0.840
Emphysema on CT 16 (10.9%) 91 (14.1%) 0.308 16 (11.0%) 18 (12.4%) 0.715
Location of pulmonary lesion (%)
 Left upper lobe 27 (18.4%) 128 (19.8%) 0.831 27 (18.7%) 31 (21.4%) 0.465
 Left lower lobe 35 (23.8%) 144 (22.2%) 34 (23.4%) 42 (29.0%)
 Right upper lobe 34 (23.1%) 174 (26.9%) 34 (23.4%) 32 (22.0%)
 Right middle lobe 12 (8.2%) 51 (7.9%) 12 (8.3%) 14 (9.7%)
 Right lower lobe 39 (26.5%) 150 (23.2%) 38 (26.2%) 26 (17.9%)
Diameter of lesion (cm) 4.8 ± 2.6 5.3 ± 2.6 0.025 4.8 ± 2.6 5.0 ± 2.4 0.582
 < 5/≥5 70/77 313/334 0.868 68/77 69/76 0.906
Proportion of necrosis in the lesion
 < 50%/≥50% 123/24 523/124 0.425 121/24 113/32 0.234
Success rate (%) 141 (95.9%) 580 (89.6%) 0.017 139 (95.9%) 128 (88.3%) 0.017
 Malignant 76 (51.7%) 393 (60.7%) < 0.001 76 (52.4%) 89 (61.4%) 0.003
 Benign 65 (44.2%) 187 (28.9%) 63 (43.5%) 39 (26.9%)
 Non-diagnostic 6 (4.1%) 67 (10.4%) 6 (4.1%) 17 (9.7%)
Complication rate (%) 12 (8.2%) 56 (8.7%) 0.847 11 (7.6%) 10 (6.9%) 0.821
 Pneumothorax 3 (2.0%) 14 (2.2%) 1.000 3 (2.1%) 4 (2.8%) 1.000
  Major 2 (1.4%) 2 (0.3%) 0.158 2 (1.4%) 1 (0.7%) 1.000
  Minor 1 (0.7%) 12 (1.9%) 0.514 1 (0.7%) 3 (2.1%) 0.615
 Hemorrhage 8 (5.5%) 44 (6.8%) 0.209 7 (4.8%) 6 (4.1%) 0.777
  Major 0 (0%) 0 (0%) 0 (0%) 0 (0%)
  Minor 8 (5.5%) 44 (6.8%) 0.548 7 (4.8%) 6 (4.1%) 0.777
 Vasovagal reaction 1 (0.7%) 0 (0%) 0.185 1 (0.7%) 0 (0%) 1.000