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Table 2 Relationship between Tumor Stroma and Clinical Features

From: Pancreatic cancer stem cells may define tumor stroma characteristics and recurrence patterns in pancreatic ductal adenocarcinoma

  Loose stroma
N (%)
Moderate stroma
N (%)
Dense stroma
N (%)
History of neoadjuvant therapy
 Yes 2 (6) 4 (8)
 No 29 (94) 47 (92) 11 (100)
History of adjuvant chemotherapy
 Yes 24 (89) 42 (84) 11 (100)
 No 3 (11) 8 (16)
History of adjuvant radiotherapy
 Yes 3 (11) 12 (24) 4 (36)
 No 25 (89) 38 (76) 7 (64)
Lymphovascular invasion
 Present 23 (74) 44 (86) 11 (100)
 Absent 8 (26) 7 (14)
Perineural invasion
 Present 28 (90) 50 (98) 10 (91)
 Absent 3 (10) 1 (2) 1 (9)
Margin status
 Positive 8 (26) 12 (24) 3 (27)
 Negative 23 (74) 39 (76) 8 (73)
Stage
 pT1 1 (3)
 pT2 0 2 (4)
 pT3 30 (97) 49 (96) 11 (100)
Node Status
 N0 11 (35) 9 (18) 2 (18)
 N1 11 (35) 19 (37) 5 (45)
 N2 9 (30) 23 (45) 4 (36)
Grade
 Well or moderately differentiated 9 (29) 24 (47) 7 (64)
 Moderate to poor, poorly differentiated 22 (71) 27 (53) 4 (36)
Cumulative dstant metastasis by site 14 (45) 33 (65) 9 (82)
- Lung 5 (15) 4 (44)
- Liver 9 (64) 18 (55) 4 (44)
- Lung + liver 4 (29) 4 (12)
- Other 1 (7) 6 (18) 1 (12)