Table 2 Relationship between Tumor Stroma and Clinical Features
Loose stroma N (%) | Moderate stroma N (%) | Dense stroma N (%) | |
|---|---|---|---|
History of neoadjuvant therapy | |||
Yes | 2 (6) | 4 (8) | – |
No | 29 (94) | 47 (92) | 11 (100) |
History of adjuvant chemotherapy | |||
Yes | 24 (89) | 42 (84) | 11 (100) |
No | 3 (11) | 8 (16) | – |
History of adjuvant radiotherapy | |||
Yes | 3 (11) | 12 (24) | 4 (36) |
No | 25 (89) | 38 (76) | 7 (64) |
Lymphovascular invasion | |||
Present | 23 (74) | 44 (86) | 11 (100) |
Absent | 8 (26) | 7 (14) | – |
Perineural invasion | |||
Present | 28 (90) | 50 (98) | 10 (91) |
Absent | 3 (10) | 1 (2) | 1 (9) |
Margin status | |||
Positive | 8 (26) | 12 (24) | 3 (27) |
Negative | 23 (74) | 39 (76) | 8 (73) |
Stage | |||
pT1 | 1 (3) | – | – |
pT2 | 0 | 2 (4) | – |
pT3 | 30 (97) | 49 (96) | 11 (100) |
Node Status | |||
N0 | 11 (35) | 9 (18) | 2 (18) |
N1 | 11 (35) | 19 (37) | 5 (45) |
N2 | 9 (30) | 23 (45) | 4 (36) |
Grade | |||
Well or moderately differentiated | 9 (29) | 24 (47) | 7 (64) |
Moderate to poor, poorly differentiated | 22 (71) | 27 (53) | 4 (36) |
Cumulative dstant metastasis by site | 14 (45) | 33 (65) | 9 (82) |
- Lung | – | 5 (15) | 4 (44) |
- Liver | 9 (64) | 18 (55) | 4 (44) |
- Lung + liver | 4 (29) | 4 (12) | – |
- Other | 1 (7) | 6 (18) | 1 (12) |