Fig. 6
From: PTEN loss correlates with T cell exclusion across human cancers
Difference of T cells infiltration between tumors with genomic gain in PIK3CA/PIK3CB and tumors with wide-type PIK3CA/PIK3CB. a Difference of T cells infiltration between tumors with PIK3CA gain and tumors with wide-type PIK3CA; b Difference of T cells infiltration between tumors with PIK3CB gain and tumors with wide-type PIK3CB. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; ns, not significant. Genomic gain in PIK3CA/PIK3CB were associated with reduced infiltration of CD8 T cell and type 1 T helper cells (Th1 cells), but increased infiltration of type 2 T helper cells (Th2 cells) in multiple cancer types. Abbreviations: full terms of cancer abbreviation were shown in Fig. 2