Fig. 7

Relationship between immunocyte infiltration and gene mutation status in the mutated gene signatures. Activated CD4 T cell and T-follicular helper cell had significant differences in all genes between mutated and non-mutated status (P < 0.05), while the distribution of CD56dim natural killer cell, monocyte and eosinophil were different in less genes. a-k Comparison of distribution of immune cells between mutation and non-mutation gene of TP53 (a), APC (b), KRAS (c), BRAF (d), ATM (e), PIK3CA (f), FAT4 (g), FMN2 (h), TRRAP (i), LRP1B (j), and ROS1 (k) in CRC patients