Fig. 3

Mutations of TP53 and BRAF were association with clinicopathological characteristics (mucinous adenocarcinoma and other adenocarcinoma). “TP53, BRAF:+,-” indicated TP53 mutated, but BRAF not; “TP53, BRAF:+,+” indicated both TP53 and BRAF mutated; “TP53, BRAF:-,+” indicated BRAF mutated, but TP53 not; “TP53, BRAF:-,-” indicated both TP53 and BRAF not mutated. a In TCGA samples, “TP53, BRAF:+,+”, “TP53, BRAF:-,+” and “TP53, BRAF:-,-” were more likely to occur in mucinous adenocarcinoma patients (red) than other adenocarcinoma patients (blue). P represents the significance of the overall difference between the four groups. b In validation samples, more than 50% mucinous adenocarcinoma patients were “TP53, BRAF:-,+”, while none of them were other adenocarcinoma. P represents the significance of the overall difference between the four groups. c The circular map and data chart of TP53 and BRAF mutation percentages in different pathological types. The outer to inner ring represents the mucinous adenocarcinoma in the validation group, other adenocarcinoma in the validation group, mucinous adenocarcinoma in the TCGA group, and other adenocarcinoma in the TCGA group