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Table 3 Univariate analysis of factors affecting cancer-specific and overall survival

From: Comparing the characteristics and predicting the survival of patients with head and neck melanoma versus body melanoma: a population-based study

Factors

5-year Cancer-Specific Survival rate

5-year Overall Survival rate

(%, mean ± SD)

(%, mean ± SD)

HNM

P value

BM

P value

HNM

P value

BM

P value

Age (CSS/OS)

 

< 0.001

 

< 0.001

 

< 0.001

 

< 0.001

  ≤ 58 / ≤63

91.5 ± 0.5

 

94.8 ± 0.2

 

88.5 ± 0.5

 

92.7 ± 0.2

 

 59–78 / 64–79

88.3 ± 0.5

 

91.6 ± 0.3

 

75.7 ± 0.8

 

81.7 ± 0.4

 

  ≥ 79 / ≥80

80.2 ± 1.1

 

82.6 ± 0.7

 

41.0 ± 1.2

 

48.8 ± 1.0

 

Sex

 

< 0.001

 

< 0.001

 

< 0.001

 

< 0.001

 Male

86.9 ± 0.4

 

90.5 ± 0.2

 

73.3 ± 0.6

 

82.7 ± 0.3

 

 Female

90.6 ± 0.6

 

94.8 ± 0.2

 

77.2 ± 0.9

 

89.7 ± 0.2

 

Race

 

0.011

 

< 0.001

 

0.366

 

< 0.001

 White

87.9 ± 0.4

 

92.8 ± 0.1

 

77.4 ± 0.5

 

86.2 ± 0.2

 

 aOthers

82.3 ± 4.7

 

80.2 ± 1.8

 

71.5 ± 5.4

 

73.5 ± 2.0

 

Histology

 

< 0.001

 

< 0.001

 

< 0.001

 

< 0.001

 NM

67.7 ± 1.4

 

72.4 ± 0.7

 

53.7 ± 1.4

 

62.1 ± 0.7

 

 LMM

96.1 ± 0.4

 

97.7 ± 0.3

 

80.2 ± 0.8

 

86.2 ± 0.8

 

 SMM

91.0 ± 0.5

 

96.8 ± 0.1

 

79.9 ± 0.7

 

91.9 ± 0.2

 

 bOther Melanoma

81.9 ± 1.3

 

86.7 ± 0.6

 

68.3 ± 1.5

 

78.6 ± 0.7

 

Thickness

 

< 0.001

 

< 0.001

 

< 0.001

 

< 0.001

  < 0.6 mm

96.8 ± 0.3

 

98.6 ± 0.1

 

84.1 ± 0.6

 

93.3 ± 0.2

 

 0.6–0.79 mm

95.1 ± 0.8

 

98.1 ± 0.2

 

80.9 ± 1.4

 

92.8 ± 0.4

 

 0.8–1.0 mm

91.0 ± 1.2

 

96.6 ± 0.3

 

78.1 ± 1.6

 

91.4 ± 0.5

 

 1.01–2.0 mm

85.9 ± 1.0

 

91.6 ± 0.4

 

72.8 ± 1.2

 

85.6 ± 0.5

 

 2.01–4.0 mm

73.2 ± 1.5

 

78.5 ± 0.8

 

58.8 ± 1.6

 

68.2 ± 0.9

 

  > 4.0 mm

58.6 ± 1.8

 

57.5 ± 1.1

 

45.1 ± 1.7

 

46.0 ± 1.1

 

Ulceration

 

< 0.001

 

< 0.001

 

< 0.001

 

< 0.001

 No

92.2 ± 0.3

 

96.5 ± 0.1

 

79.1 ± 0.5

 

90.9 ± 0.2

 

 Yes

64.3 ± 1.4

 

69.1 ± 0.7

 

50.3 ± 1.4

 

58.5 ± 0.7

 

Stage

 

< 0.001

 

< 0.001

 

< 0.001

 

< 0.001

 Localized

92.7 ± 0.3

 

96.4 ± 0.1

 

78.7 ± 0.5

 

90.0 ± 0.2

 

 Regional

61.7 ± 1.6

 

65.5 ± 0.9

 

51.0 ± 1.6

 

58.2 ± 0.9

 

 Distant

36.6 ± 4.2

 

30.5 ± 2.4

 

28.4 ± 3.8

 

26.0 ± 2.3

 

Metastases

 

< 0.001

 

< 0.001

 

< 0.001

 

< 0.001

 No

88.7 ± 0.4

 

93.2 ± 0.1

 

75.1 ± 0.5

 

86.7 ± 0.2

 

 Yes

30.1 ± 4.5

 

20.3 ± 2.4

 

23.8 ± 4.2

 

17.6 ± 2.2

 

Surgery

 

0.002

 

0.061

 

< 0.001

 

< 0.001

 No

82.0 ± 3.0

 

91.6 ± 1.2

 

60.8 ± 3.8

 

80.7 ± 1.7

 

 Yes

88.0 ± 0.4

 

92.6 ± 0.2

 

74.7 ± 0.5

 

86.1 ± 0.2

 
  1. HNM head and neck melanoma, BM body melanoma, SD standard deviation, CSS cancer-specific survival, OS overall survival, NM nodular melanoma, LMM Lentigo maligna melanoma, SSM superficial spreading melanoma
  2. a Others = black, Asian or pacific islander, American indian/Alaska native
  3. b Other melanoma: International Classification of Diseases for Oncology-O-3, codes 8722–8723, 8730, 8740–8741, 8744–8746, 8761, 8770–8774, 8780
  4. P values were obtained using the log-rank test. Bold values indicate statistical significance less than 0.05
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BMC Cancer

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