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Table 1 Characteristics of the enrolled studies on AXIN2 Polymorphism and cancer

From: New insights of the correlation between AXIN2 polymorphism and cancer risk and susceptibility: evidence from 72 studies

Polymorphism First author Year Ethnicity Genotyping Method Source of Control Cancer Type Cases Controls
PAA PAB PBB HAA HAB HBB HWE
rs11079571 Wang et al. 2008 Caucasion GoldenGate PB Breast Cancer 32 233 533 16 221 606 Y
rs11079571 Alanazi et al. 2013 Asian TaqMan PB Breast Cancer 182 194 55 11 37 45 Y
rs11079571 Zhang et al. 2015 Asian PCR PB Acute Leukemia 196 180 201 42 170 189 Y
rs1133683 Gunes et al. 2009 Asian PCR PB Lung Cancer 172 204 10 42 50 8 Y
rs1133683 Pinarbasi et al. 2010 Asian PCR HB Prostate Cancer 724 872 6 44 48 8 Y
rs1133683 Gunes et al. 2010 Asian PCR HB Astrocytoma 70 306 20 42 50 8 Y
rs1133683 Davoodi et al. 2015 Asian PCR-RFLP PB Ovarian Cancer 386 1210 6 58 34 8 Y
rs1133683 Rosales-Reynoso et al. 2016 Caucasion PCR-RFLP PB Colorectal Cancer 124 252 19 22 57 21 Y
rs1133683 Bahl et al. 2017 Asian PCR-RFLP PB Lung Cancer 190 1406 37 103 169 33 N
rs2240307 Gunes et al. 2009 Asian PCR PB Lung Cancer 96 4 0 95 5 0 Y
rs2240307 Pinarbasi et al. 2010 Asian PCR HB Prostate Cancer 81 3 0 98 2 0 Y
rs2240307 Gunes et al. 2010 Asian PCR HB Astrocytoma 93 7 0 95 5 0 Y
rs2240307 Filho et al. 2011 Caucasion TaqMan HB Oral Cancer PA = 182 PB = 194 HA = 212 HB = 238 NA
rs2240307 Han et al. 2016 Asian PCR PB Lung Cancer 63 27 12 79 36 5 Y
rs2240307 Bahl et al. 2017 Asian PCR-RFLP PB Lung Cancer 342 34 0 289 16 0 Y
rs2240308 Kanzaki et al. 2006 Asian PCR-RFLP PB Colorectal Cancer 54 44 15 42 52 15 Y
rs2240308 Kanzaki et al. 2006 Asian PCR-RFLP PB Head and neck Cancer 25 29 9 42 52 15 Y
rs2240308 Kanzaki et al. 2006 Asian PCR-RFLP PB Lung Cancer 81 71 8 42 52 15 Y
rs2240308 Gunes et al. 2009 Asian PCR PB Lung Cancer 45 47 8 32 52 16 Y
rs2240308 Gunes et al. 2010 Asian PCR HB Astrocytoma 39 45 16 32 52 16 Y
rs2240308 Ferna’ndez-Rozadilla et al. 2010 Caucasion MassARRAY HB Colorectal Cancer 252 423 168 290 442 152 Y
rs2240308 Pinarbasi et al. 2010 Asian PCR HB Prostate Cancer 30 35 19 34 48 18 Y
rs2240308 Naghibalhossaini et al. 2011 Asian PCR-RFLP PB Colorectal Cancer 34 57 19 55 98 26 Y
rs2240308 Filho et al. 2011 Caucasion TaqMan HB Oral Cancer PA = 196 PB = 180 HA = 226 HB = 226 NA
rs2240308 Mostowska et al. 2013 Caucasion PCR-RFLP HB Ovarian Cancer 67 115 46 71 146 65 Y
rs2240308 Liu et al. 2014 Asian PCR PB Lung Cancer 235 216 47 211 255 67 Y
rs2240308 Ma et al. 2014 Asian PCR HB Prostate Cancer 61 31 11 39 52 9 Y
rs2240308 Aristizabal-Pachon et al. 2015 Caucasion PCR-RFLP PB Breast Cancer 20 58 24 44 55 3 N
rs2240308 Yadav et al. 2015 Asian PCR-RFLP PB Gallbladder Cancer 98 108 44 192 253 119 N
rs2240308 Rosales-Reynoso et al. 2016 Caucasion PCR-RFLP PB Colorectal Cancer 25 109 54 22 59 18 Y
rs2240308 Kim et al. 2016 Asian GoldenGate HB Hepatocellular Carcinoma 124 100 18 246 195 41 Y
rs2240308 Han et al. 2016 Asian PCR PB Lung Cancer 50 34 18 67 43 10 Y
rs2240308 Kim et al. 2016 Asian Dynamic 96.96 ArrayTM Assay PB Lung Cancer 169 142 47 562 436 124 N
rs2240308 Liu et al. 2016 Asian MassARRAY HB Papillary Thyroid Carcinoma 27 24 2 17 29 4 Y
rs2240308 Bahl et al. 2017 Asian PCR-RFLP PB Lung Cancer 99 150 54 81 144 80 Y
rs35285779 Gunes et al. 2009 Asian PCR PB Lung Cancer 77 20 3 64 28 8 Y
rs35285779 Pinarbasi et al. 2010 Asian PCR HB Prostate Cancer 69 15 0 61 32 7 Y
rs35285779 Gunes et al. 2010 Asian PCR HB Astrocytoma 70 25 5 64 28 8 Y
rs35285779 Bahl et al. 2017 Asian PCR-RFLP PB Lung Cancer 255 46 2 248 55 2 Y
rs35415678 Gunes et al. 2009 Asian PCR PB Lung Cancer 91 9 0 86 14 0 Y
rs35415678 Pinarbasi et al. 2010 Asian PCR HB Prostate Cancer 83 1 0 99 1 0 Y
rs35415678 Gunes et al. 2010 Asian PCR HB Astrocytoma 87 13 0 86 14 0 Y
rs35415678 Bahl et al. 2017 Asian PCR-RFLP PB Lung Cancer 257 46 0 261 44 0 Y
rs3923086 Wang et al. 2008 Caucasion GoldenGate PB Breast Cancer 238 395 164 284 419 139 Y
rs3923086 Filho et al. 2011 Caucasion TaqMan HB Oral Cancer PA = 172 PB = 204 HA = 212 HB = 238 NA
rs3923086 Alanazi et al. 2013 Asian TaqMan PB Breast Cancer 27 41 31 16 42 35 Y
rs3923086 Liu et al. 2016 Asian MassARRAY HB Papillary Thyroid Carcinoma 47 8 0 34 15 1 Y
rs3923086 Parine et al. 2019 Asian TaqMan PB Colorectal Cancer 48 52 21 41 50 19 Y
rs3923087 Wang et al. 2008 Caucasion GoldenGate PB Breast Cancer 47 292 458 39 278 525 Y
rs3923087 Filho et al. 2011 Caucasion TaqMan HB Oral Cancer PA = 70 PB = 306 HA = 130 HB = 320 NA
rs3923087 Mostowska et al. 2013 Caucasion PCR-RFLP HB Ovarian Cancer 10 84 133 14 97 171 Y
rs3923087 Alanazi et al. 2013 Asian TaqMan PB Breast Cancer 45 35 18 24 50 19 Y
rs3923087 Parine et al. 2019 Asian TaqMan PB Colorectal Cancer 35 56 32 37 50 23 Y
rs4072245 Gunes et al. 2009 Asian PCR PB Lung Cancer 73 27 0 80 20 0 Y
rs4072245 Pinarbasi et al. 2010 Asian PCR HB Prostate Cancer 73 11 0 78 22 0 Y
rs4072245 Gunes et al. 2010 Asian PCR HB Astrocytoma 82 18 0 80 20 0 Y
rs4791171 Wang et al. 2008 Caucasion GoldenGate PB Breast Cancer 83 332 383 61 349 433 Y
rs4791171 Filho et al. 2011 Caucasion TaqMan HB Oral Cancer PA = 124 PB = 252 HA = 136 HB = 316 NA
rs4791171 Alanazi et al. 2013 Asian TaqMan PB Breast Cancer 34 44 21 22 44 17 Y
rs4791171 Yadav et al. 2015 Asian PCR-RFLP PB Gallbladder Cancer 35 118 97 88 248 228 Y
rs4791171 Parine et al. 2019 Asian TaqMan PB Colorectal Cancer 40 55 27 38 48 24 Y
rs7219582 Gunes et al. 2009 Asian PCR PB Lung Cancer 97 3 0 96 4 0 Y
rs7219582 Pinarbasi et al. 2010 Asian PCR HB Prostate Cancer 81 3 0 95 5 0 Y
rs7219582 Gunes et al. 2010 Asian PCR HB Astrocytoma 91 9 0 96 4 0 Y
rs7219582 Bahl et al. 2017 Asian PCR-RFLP PB Lung Cancer 87 205 11 42 263 0 N
rs7224837 Filho et al. 2011 Caucasion TaqMan HB Oral Cancer 342 34   400 50   NA
rs7224837 Mostowska et al. 2013 Caucasion PCR-RFLP HB Ovarian Cancer 161 61 6 203 71 8 Y
rs7224837 Jeanne et al. 2015 Caucasion iSelect genotyping array HB Bladder Cancer 646 151 6 616 169 17 Y
rs9915936 Gunes et al. 2009 Asian PCR PB Lung Cancer 91 9 0 88 12 0 Y
rs9915936 Pinarbasi et al. 2010 Asian PCR HB Prostate Cancer 77 7 0 92 8 0 Y
rs9915936 Gunes et al. 2010 Asian PCR HB Astrocytoma 91 9 0 88 12 0 Y
rs9915936 Bahl et al. 2017 Asian PCR-RFLP PB Lung Cancer 268 29 6 249 51 5 Y
  1. HB Hospital Based, PB Population Based, HWE Hardy Weinberg Equilibrium, Y polymorphisms conformed to HWE in the control group, N polymorphisms didn’t conform to HWE in the control group, NA not available