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Fig. 6 | BMC Cancer

Fig. 6

From: Mesenchymal stem cells accelerated growth and metastasis of neuroblastoma and preferentially homed towards both primary and metastatic loci in orthotopic neuroblastoma model

Fig. 6

The “positive” and “anti-cancer” effects of MSCs on neuroblastoma. MSCs exhibited potent effects on accelerating the potency of tumor formation, growth and metastasis in vivo. On the other hand, intravenous infused MSCs could be recruited by both primary tumor and metastatic loci, which could be reduced when MSCs were pre-treated with SDF-1 blocker, AMD3100. The preferentially homing propensity of MSCs provides new therapeutic insights in utilizing bio-engineered MSCs as vehicles for targeted anti-cancer therapy against advanced cancers

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BMC Cancer

ISSN: 1471-2407

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