Fig. 3
From: Gene expression and immune infiltration in melanoma patients with different mutation burden
Differentially expression analysis and Construction of TMB-IP. a Top 50 DEGs were displayed in heatmap plot; b GO results of 504 DEGs; c GSEA revealed the top TMB- associated pathways revealed that low-TMB was correlated with immune-related pathways; d Survival analysis based on the immunescore; e-g Univariate-lasso-multivariate Cox regression of 38 immune-related DEGs; h Survival analysis based on the TMB-IP score; i Multi-year ROC curves based on the TMB-IP score; j-m Survival analysis of four immune-related hub genes based on their RNA expression levels; n-s Survival analysis of six clinical subgroups based on high and low TMB-IP grouping