Fig. 1
Expression of SOX2, P16INK4A, and HR-HPV RISH in SCNEC. a Immunohistochemical staining showing the SOX2 level in tissue microarray (TMA), with negative, weak, moderate, and strong intensity staining. b Negative and positive immunohistochemical staining for P16INK4A expression in tumor tissues. c HPV mRNA was detected using HR-HPV RISH in tumor tissues (T). Representative images of scores 0 (T0), 1 (T1), 2 (T2), 3 (T3), and 4 (T4) are shown. d The proportion of HR-HPV RISH scores in SCNEC tissues