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Table 5 Multivariate Cox Regression Analysis

From: TIM3 expression on TILs is associated with poor response to neoadjuvant chemotherapy in patients with locally advanced triple-negative breast cancer

 

Disease Free

Survival

 

Disease Specific

Survival

 

Factors

HR (95%CI)

P value

HR (95%CI)

P value

ypN

 

0.02

 

0.005

N0

0.31 (0.12–0.83)

 

0.21 (0.07–0.62)

 

N1–3

Reference [1]

 

Reference [1]

 

CTLA-4

 

0.019

 

0.01

Low

Reference [1]

 

Reference [1]

 

Higha

0.38 (0.17–0.85)

 

0.34 (0.15–0.78)

 
  1. Cox Regression (Step-2, Method = Forward Stepwise)
  2. Variables not in the Equation: PDL-1(<%1 vs ≥ %1), MDACC Residual Cancer Burden Index (Class 0 vs Class I-III)
  3. Hazard ratio (HR) are presented with their 95% confidence interval (CI) and the p-value
  4. a > 15% & any moderate/strong staining if < 15%