Skip to main content

Table 1 Spearman correlations (SC) of the immune checkpoint receptor (=ICR) expressions in TILs (n = 61)

From: TIM3 expression on TILs is associated with poor response to neoadjuvant chemotherapy in patients with locally advanced triple-negative breast cancer

   PDL-1 PDL-1tumor PD1 LAG3 TIM3 CTLA-4TILs CTLA-4TM
PDL-1tumor r 0.772       
P-value < 0.001**       
n 48       
PD1 r 0.354 0.352      
P-value 0.007** 0.014*      
n 57 48      
LAG3 r 0.370 0.476 0.174     
P-value 0.005** 0.001** 0.179     
n 57 48 61     
TIM3 r 0.256 0.236 0.407 0.274    
P-value 0.055 0.106 0.001** 0.033*    
n 57 48 61 61    
CTLA-4TILs r 0.148 0.068 0.460 0.037 0.301   
P-value 0.272 0.648 < 0.001** 0.776 0.018*   
n 57 48 61 61 61   
CTLA-4TM r 0.131 0.106 0.248 0.251 0.277 0.486  
P-value 0.374 0.472 0.076 0.073 0.047* < 0.001**  
n 48 48 52 52 52 52  
MDACC Score r −0.061 −0.010 0.153 −0.061 0.062 0.008 0.119
P-value 0.653 0.947 0.244 0.645 0.637 0.953 0.405
n 56 47 60 60 60 60 51
  1. *p < 0.05, **p < 0.01, r: Spearman Correlations
  2. MDARB-Index: MD Anderson Residual Cancer Burden Index
\