| Univariate analysis | Multivariate analysis (n = 112) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
variables | n | estimates | S.E. | HR | 95% CI | p | estimates | S.E. | HR | 95% CI | p |
QLQ-C15-PAL | |||||||||||
 Physical Functioning | 125 | −0.001 | 0.004 | 0.999 | 0.991–1.006 | .738 |  |  |  |  |  |
 Emotional Functioning | 129 | 0.001 | 0.003 | 1.001 | 0.994–1.008 | .809 |  |  |  |  |  |
 Dyspnea | 130 | 0.010 | 0.003 | 1.010 | 1.005–1.016 | < .001** | 0.012 | 0.003 | 1.012 | 1.005–1.019 | < .001** |
 Pain | 129 | −0.0004 | 0.003 | 1.000 | 0.994–1.005 | .878 |  |  |  |  |  |
 Insomnia | 130 | 0.001 | 0.003 | 1.001 | 0.996–1.006 | .608 |  |  |  |  |  |
 Appetite Loss | 130 | 0.005 | 0.003 | 1.005 | 1.000–1.010 | .073 |  |  |  |  |  |
 Constipation | 128 | 0.0003 | 0.003 | 1.000 | 0.995–1.006 | .922 |  |  |  |  |  |
 Fatigue | 129 | 0.011 | 0.003 | 1.011 | 1.004–1.017 | .002** | 0.009 | 0.004 | 1.009 | 1.001–1.016 | .024* |
 Nausea/Vomiting | 130 | 0.002 | 0.003 | 1.002 | 0.995–1.008 | .597 |  |  |  |  |  |
 QOL | 124 | −0.007 | 0.004 | 0.993 | 0.986–1.000 | .055 |  |  |  |  |  |
Inflammatory Biomarkers | |||||||||||
 CRP | 126 | 0.049 | 0.014 | 1.050 | 1.022–1.079 | < .001** |  |  |  |  |  |
 Alb | 126 | −0.465 | 0.171 | 0.628 | 0.449–0.878 | .007** | −0.457 | 0.180 | 0.633 | 0.445–0.902 | .011* |
 NLR | 122 | 0.017 | 0.003 | 1.017 | 1.012–1.023 | < .001** | 0.015 | 0.003 | 1.015 | 1.009–1.021 | < .001** |