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Table 2 Results of Cox proportional hazard model analysis of survival data

From: The role of EORTC QLQ-C15-PAL scores and inflammatory biomarkers in predicting survival in terminally ill patients with cancer

 

Univariate analysis

Multivariate analysis (n = 112)

variables

n

estimates

S.E.

HR

95% CI

p

estimates

S.E.

HR

95% CI

p

QLQ-C15-PAL

 Physical Functioning

125

−0.001

0.004

0.999

0.991–1.006

.738

     

 Emotional Functioning

129

0.001

0.003

1.001

0.994–1.008

.809

     

 Dyspnea

130

0.010

0.003

1.010

1.005–1.016

< .001**

0.012

0.003

1.012

1.005–1.019

< .001**

 Pain

129

−0.0004

0.003

1.000

0.994–1.005

.878

     

 Insomnia

130

0.001

0.003

1.001

0.996–1.006

.608

     

 Appetite Loss

130

0.005

0.003

1.005

1.000–1.010

.073

     

 Constipation

128

0.0003

0.003

1.000

0.995–1.006

.922

     

 Fatigue

129

0.011

0.003

1.011

1.004–1.017

.002**

0.009

0.004

1.009

1.001–1.016

.024*

 Nausea/Vomiting

130

0.002

0.003

1.002

0.995–1.008

.597

     

 QOL

124

−0.007

0.004

0.993

0.986–1.000

.055

     

Inflammatory Biomarkers

 CRP

126

0.049

0.014

1.050

1.022–1.079

< .001**

     

 Alb

126

−0.465

0.171

0.628

0.449–0.878

.007**

−0.457

0.180

0.633

0.445–0.902

.011*

 NLR

122

0.017

0.003

1.017

1.012–1.023

< .001**

0.015

0.003

1.015

1.009–1.021

< .001**

  1. *p < .05, **p < .01; estimates = regression coefficients, S.E.: Standard errors of estimates; all QLQ-C15-PAL scale scores were linearly transformed, and the resultant scores ranged from 0 to 100. Alb albumin, CI confidence interval, CRP C-reactive protein, HR hazard ratio, NLR neutrophil-lymphocyte ratio, QLQ-C15-PAL European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 Palliative Care, QOL quality of life
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BMC Cancer

ISSN: 1471-2407

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