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Table 2 Effects of baseline characteristics and skin conditions bothered by skin symptoms and signs in patients

From: Radiation-irritated skin and hyperpigmentation may impact the quality of life of breast cancer patients after whole breast radiotherapy

Factor

Yes

No

p-value*#

a

Bother of dry skin

Sweating in the radiation field

  

0.0042*

 Absent sweating and hotness

102 (71.83)

40 (28.17)

 Absent sweating

89 (47.09)

100 (52.91)

 Normal

20 (22.22)

70 (77.78)

Dryness in the radiation field

  

<.0001*

 Dry skin and itchy

142 (77.17)

42 (22.83)

 Dry skin

66 (42.31)

90 (57.69)

 Normal

3 (3.70)

78 (96.30)

Seasonal skin irritation

  

0.0796

 Yes

138 (72.25)

53 (27.75)

 No

73 (31.74)

157 (68.26)

History of post-RT severe skin disorder

  

0.0193*

 Yes

57 (75.00)

19 (25.00)

 No

154 (44.64)

191 (55.36)

Skin color deposition

  

<.0001*

 Severe

82 (73.21)

30 (26.79)

 Mild

111 (49.55)

113 (50.45)

 None

18 (21.18)

67 (78.82)

Interval after radiotherapy, months

  

0.1609

  < 1

22 (50.00)

22 (50.00)

 1–6

53 (48.62)

56 (51.38)

 6–12

53 (58.24)

38 (41.76)

 12–24

48 (51.61)

45 (48.39)

  > 24

35 (41.67)

49 (58.33)

b

Depression due to the skin problems

Interval after radiotherapy, months

  

0.0446*

  < 1

7 (15.91)

37 (84.09)

 1–6

21 (19.27)

88 (80.73)

 6–12

19 (20.88)

72 (79.12)

 12–24

24 (25.81)

69 (74.19)

  > 24

18 (21.43)

66 (78.57)

Sweating in the radiation field

  

0.0002*

 Absent sweating and hotness

52 (36.62)

90 (63.38)

 Absent sweating

29 (15.34)

160 (84.66)

 Normal

8 (8.89)

82 (91.11)

Dryness in the radiation field

  

0.1349

 Dry skin and itch

48 (26.09)

136 (73.91)

 Dry skin

35 (22.44)

121 (77.56)

 Normal

6 (7.41)

75 (92.59)

Skin color deposition

  

0.0008*

 Severe

38 (33.93)

74 (66.07)

 Mild

47 (20.98)

177 (79.02)

 None

4 (4.71)

81 (95.29)

  1. Abbreviation: RT, Radiotherapy
  2. *: A p-value less than 0.05 indicates that the factor affects the bother of skin symptoms
  3. #: Wald chi-square test
  4. *: A p-value less than 0.05 indicates that the factor affects the bother of skin symptoms
  5. #: Wald chi-square test