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Table 2 Lymph node count and adequate lymph node ratio

From: A greater lymph node yield is required during pathological examination in microsatellite instability-high gastric cancer

 

Lymph node harvest of MSI-H GC

Lymph node harvest of MSS GC

p value

Adequate ratio

Median (quartile)

Adequate ratio

Median (quartile)

Adequate ratio

Median (quartile)

All patients

95.1%

30(23–38)

91.9%

28(21–37)

0.145

0.031

Distal gastrectomy

95.6%

30(23–38)

91.2%

27(20–35)

0.061

0.002

Total gastrectomy

91.7%

30(25–39)

94.2%

30(22–41)

0.647

0.962

With NAdj therapy

95.0%

36(30–44)

93.4%

34(24–44)

1.000

0.395

W/out NAdj therapy

95.2%

29(23–38)

91.7%

27(20–36)

0.129

0.034

For Distal gastrectomy only

 AJCC Stage

  I

94.6%

27(21–33)

88.7%

24(19–33)

0.246

0.200

  II

98.0%

34(26–42)

88.4%

28(19–36)

0.052

0.005

  III

96.1%

31(25–38)

95.1%

29(23–37)

1.000

0.278

  IV

N.A.

N.A.

94.1%

28(20–39)

N.A.

N.A.

 T category

  Tis and T1

94.6%

25(19–33)

89.5%

26(19–30)

0.563

0.985

  T2

97.1%

33(23–42)

89.2%

27(20–36)

0.206

0.056

  T3

96.6%

35(26–41)

97.6%

30(24–37)

1.000

0.071

  T4

94.9%

31(24–38)

92.5%

28(22–37)

0.783

0.086

 N category

  N0

95.0%

28(22–36)

88.0%

24(19–33)

0.078

0.002

  N+

96.2%

31(24–38)

93.8%

28(22–37)

0.607

0.083

For Total gastrectomy only

 AJCC Stage

  I

93.3%

26(17–30)

80.0%

26(20–34)

0.172

0.480

  II

100.0%

37(27–46)

97.4%

30(21–41)

1.000

0365

  III

100.0%

37(29–39)

94.8%

32(24–43)

0.364

0.618

  IV

N.A.

N.A.

86.7%

29(19–43)

N.A.

N.A.

 T category

  Tis and T1

75.0%

24(16–28)

94.3%

28(21–35)

0.104

0.122

  T2

100.0%

26(26–40)

95.9%

27(20–35)

1.000

0.277

  T3

100.0%

39(36–41)

96.1%

32(24–43)

1.000

0.273

  T4

100.0%

30(27–42)

93.4%

32(22–43)

1.000

0.839

 N category

  N0

92.3%

26(21–42)

93.4%

28(20–37)

0.602

0.738

  N+

90.9%

32(29–39)

94.5%

32(23–43)

0.472

0.995

  1. MSI microsatellite instability
  2. MSS microsatellite stability
  3. GC gastric cancer
  4. W/out without
  5. NAdj neoadjuvant
  6. N.A. not applicable