Fig. 5

Eppk1 affects EGFR expression and p38 signal pathway. a Correlation analysis between mRNA level of Eppk1 and EGFR in CSCC tissues from TCGA database. b Ad-GFP and Ad-KLF5-infected HeLa cells and Ad-KLF5-infected HeLa cells were transfected with si-Eppk1 for 36 h. Western blot was used to decide the activation of AKT, ERK1/2 and p38 signaling. c Band intensities were measured and normalized to β-actin or total AKT, ERK1/2 and P38 (n = 3). *P < 0.05 and **P < 0.01 vs. control, ^#P < 0.05 vs. Ad-GFP