Table 4 GO functional annotation for genes green modules
From: Identification of the potential novel biomarkers as susceptibility gene for Wilms tumor
Series | Name | P-value | Adjusted p-value | Z-score | Combined score | GENE |
|---|---|---|---|---|---|---|
GO Biological process | excitatory postsynaptic potential (GO:0060079) | 0.0004911 | 0.08474 | −2.92 | 22.27 | MAPK8IP2;GRIN1 |
GO Biological process | regulation of NMDA receptor activity (GO:2000310) | 0.0007466 | 0.08474 | −3.46 | 24.95 | DLG4;MAPK8IP2 |
GO Celluar Component | excitatory synapse (GO:0060076) | 0.0008938 | 0.03972 | −2.75 | 19.28 | DLG4;GRIN1 |
GO Celluar Component | postsynaptic density (GO:0014069) | 0.001281 | 0.03972 | −3.05 | 20.29 | DLG4;MAPK8IP2;GRIN1 |
GO Biological process | calcium ion homeostasis (GO:0055074) | 0.001819 | 0.1033 | −2.92 | 18.41 | TRPV6;GRIN1 |
GO Biological process | positive regulation of excitatory postsynaptic potential (GO:2000463) | 0.001819 | 0.1033 | −2.31 | 14.54 | DLG4;GRIN1 |
GO Biological process | stress-activated MAPK cascade (GO:0051403) | 0.003053 | 0.1372 | −2.45 | 14.17 | TAOK2;MAP 2 K7 |
GO Biological process | phosphatidylinositol 3-kinase signaling (GO:0014065) | 0.004254 | 0.1372 | −2.45 | 13.38 | LTK;PIK3CD |
GO Biological process | signal transduction (GO:0007165) | 0.004805 | 0.1372 | −6.49 | 34.63 | PSD;CACNA1I;LTK;EPO;DLG4;PIK3CD;IGFALS;RASGRP2;MAP 2 K7 |
GO Celluar Component | postsynaptic membrane (GO:0045211) | 0.006795 | 0.1289 | −2.47 | 12.32 | DLG4;GRIN1 |
GO Molecular Function | triglyceride lipase activity (GO:0004806) | 0.007203 | 0.2384 | −1.95 | 9.61 | CES1P1;PNPLA2 |