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Table 4 Birth weight and length: associations with luminal and non-luminal breast cancer, by maternal height

From: The association of women’s birth size with risk of molecular breast cancer subtypes: a cohort study

  Luminal subtypes Non-luminal subtypes
Maternal height < 163 cm Maternal height ≥ 163 cm Maternal height < 163 cm Maternal height ≥ 163 cm
Cases Incidence rateb HR (95% CI)a Cases Incidence rateb HR (95% CI)a Cases Incidence rateb HR (95% CI)a Cases Incidence rateb HR (95% CI)a
Birth weight (g)
  < 3000 32 37.2 1.0 (0.6–1-5) 24 35.2 1.0 (0.6–1.6) 6 7.0 1.0 (0.3–3.3) 3 4.4 0.5 (0.1–2.5)
 3000–3499 82 42.5 1.0 (ref) 71 37.2 1.0 (ref) 10 5.2 1.0 (ref) 10 5.2 1.0 (ref)
 3500–3999 81 56.5 1.3 (1.0–1.8) 74 36.7 1.0 (0.7–1.4) 4 2.8 0.5 (0.2–1.7) 11 5.5 1.1 (0.5–2.7)
  ≥ 4000 21 45.2 1.0 (0.6–1.6) 33 38.3 1.1 (0.7–1.7) 3 6.5 1.1 (0.3–4.2) 5 5.8 1.3 (0.4–3.8)
 Per 500 g 216 46.0 1.1 (0.9–1.3) 202 36.9 1.1 (0.9–1.3) 23 4.9 0.7 (0.7–1.6) 29 5.3 1.3 (0.9–1.9)
Birth length (cm)c,d
  < 49 33 43.9 1.0 (ref) 17 31.2 1.0 (ref) 6 8.0 1.0 (ref) 2 3.7 1.0
 49 29 40.5 0.8 (0.5–1.4) 14 23.8 0.8 (0.4–1.6) 4 5.6 0.9 (0.2–3.5) 2 3.4 1.9 (0.2–11.0)
 50 63 54.8 1.1 (0.7–1.6) 40 34.9 1.1 (0.6–2.1) 7 6.1 0.9 (0.3–3.1) 5 4.4 2.4 (0.3–18.0)
 51 35 40.4 0.9 (0.5–1.4) 41 37.2 1.3 (0.7–2.5) 3 3.5 0.7 (0.1–3.0) 6 5.5 3.5 (0.5–26.3)
  ≥ 52 56 46.4 1.0 (0.6–1.6) 90 43.1 1.6 (0.9–2.9) 3 2.5 0.5 (0.1–2.5) 14 6.7 4.4 (0.6–30.6)
 Per 2 cm 216 46.0 1.0 (0.9–1.2) 202 36.9 1.3 (1.1–1.5) 23 4.9 1.0 (0.7–1.6) 29 5.3 1.5 (1.0–2.2)
  1. aHRs adjusted for gestational age at birth, birth order, birth year in 5 year categories, maternal age at birth, and maternal socioeconomic status
  2. bPer 100,000 person years
  3. cLikelihood-ratio test for the association of birth length with luminal subtypes of breast cancer according to maternal height, p = 0.7
  4. dLikelihood-ratio test for the association of birth length with non-luminal subtypes of breast cancer according to maternal height, p = 0.4