Table 2 Descriptive statistics for the 537 breast cancer cases with molecular subtyping
From: The association of women’s birth size with risk of molecular breast cancer subtypes: a cohort study
Luminal A | Luminal B (HER-) | Luminal B (HER+) | HER 2 type | Triple negative | Total | |
|---|---|---|---|---|---|---|
Number (%) | 232 (43.2) | 175 (32.6) | 65 (12.1) | 24 (4.5) | 41 (7.6) | 537 (100) |
Mean age at diagnosis (SD) | 56.4 (9.8) | 54.1 (11.3) | 53.8 (9.8) | 51.5 (10.7) | 53.9 (11.3) | 54.9 (10.5) |
Tumour grade (%) | ||||||
1 | 58 (25.0) | 3 (1.7) | 1 (1.5) | 1 (4.2) | 0 | 63 (11.7) |
2 | 155 (66.8) | 93 (53.1) | 19 (29.2) | 3 (12.5) | 6 (14.6) | 276 (51.4) |
3 | 19 (8.2) | 79 (45.1) | 45 (69.2) | 20 (83.3) | 35 (85.4) | 198 (36.9) |
Histopathological type | ||||||
Ductal | 198 (85.3) | 155 (88.6) | 60 (92.3) | 18 (75.0) | 31 (75.6) | 462 (86.0) |
Lobular | 24 (10.3) | 8 (4.6) | 2 (3.1) | 0 | 0 | 34 (6.3) |
Tubular | 2 (0.9) | 0 | 0 | 0 | 0 | 2 (0.4) |
Mucinous | 6 (2.6) | 2 (1.1) | 0 | 0 | 0 | 8 (1.5) |
Medullary | 0 | 6 (3.4) | 3 (4.6) | 6 (25.0) | 6 (14.6) | 21 (3.9) |
Papillary | 0 | 1 (0.6) | 0 | 0 | 0 | 1 (0.2) |
Metaplastic | 0 | 0 | 0 | 0 | 2 (4.9) | 2 (0.4) |
Other | 2 (0.9) | 3 (1.7) | 0 | 0 | 2 (4.9) | 7 (1.3) |
Tumour size, cm (%) | ||||||
< 2 | 151 (65.1) | 79 (45.1) | 26 (40.0) | 4 (16.7) | 14 (34.2) | 274 (51.0) |
2–5 | 49 (21.1) | 59 (33.7) | 28 (43.1) | 10 (41.7) | 16 (39.0) | 162 (30.2) |
> 5 | 5 (2.2) | 7 (4.0) | 1 (1.5) | 0 | 2 (4.9) | 15 (2.8) |
Uncertain | 27 (11.6) | 30 (17.1) | 10 (15.4) | 10 (41.7) | 9 (22.0) | 86 (16.0) |
Stage | ||||||
0 | 0 | 0 | 0 | 1 (4.2) | 0 | 1 (0.2) |
I | 105 (45.3) | 57 (32.6) | 14 (21.5) | 8 (33.3) | 17 (41.5) | 201 (37.4) |
II | 92 (39.7) | 90 (51.4) | 37 (56.9) | 12 (50.0) | 14 (34.2) | 245 (45.6) |
III | 10 (4.3) | 8 (4.6) | 3 (4.6) | 1 (4.2) | 3 (7.3) | 25 (4.7) |
IV | 4 (1.7) | 4 (2.3) | 4 (6.2) | 1 (4.2) | 1 (2.4) | 12 (2.6) |
Unknown | 21 (9.1) | 16 (9.1) | 7 (10.8) | 1 (4.2) | 6 (14.6) | 51 (9.5) |