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Table 2 Subjects’ Characteristics of Validation Study

From: A prediction model based on DNA methylation biomarkers and radiological characteristics for identifying malignant from benign pulmonary nodules

Characteristics Subjects with Malignant PNs
(n = 57)
Subjects with Benign PNs
(n = 43)
Clinical
Age (Years)
  Median Age 62 54
  Age Range 38–78 27–72
Sex
  Male 39 29
  Female 18 14
Smoking history
  Non-smoker 25 30
  Ex-smoker 12 4
  Current smoker 20 9
Smoking pack years
  Mean Pack-years (Smokers only) 40.77 21.64
  Years quit (Smoker sonly) 7.35 3.75
Histology subtype
  Adenocarcinoma 32  
  Squamous cell carcinoma 14  
  Small cell lung cancer 2  
  Other 9  
Stage
  I 18  
  II 20  
  III-IV 19  
Radiological
  Nodule size (mm) 21.83 (SD 10.88) 11.22 (SD 7.56)
Nodule location
  Left lower lobe 12 10
  Left upper lobe 12 10
  Right lower lobe 11 11
  Right middle lobe 5 4
  Right upper lobe 17 8
Nodule type (number)
  Nonsolid or ground-glass opacity 17 13
  Perifissural 8 6
  Part-solid 9 7
  Solid 13 10
  Spiculation 10 7
  1. PN pulmonary nodule, SD standard deviation