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Table 2 Subjects’ Characteristics of Validation Study

From: A prediction model based on DNA methylation biomarkers and radiological characteristics for identifying malignant from benign pulmonary nodules

Characteristics

Subjects with Malignant PNs

(n = 57)

Subjects with Benign PNs

(n = 43)

Clinical

Age (Years)

  Median Age

62

54

  Age Range

38–78

27–72

Sex

  Male

39

29

  Female

18

14

Smoking history

  Non-smoker

25

30

  Ex-smoker

12

4

  Current smoker

20

9

Smoking pack years

  Mean Pack-years (Smokers only)

40.77

21.64

  Years quit (Smoker sonly)

7.35

3.75

Histology subtype

  Adenocarcinoma

32

 

  Squamous cell carcinoma

14

 

  Small cell lung cancer

2

 

  Other

9

 

Stage

  I

18

 

  II

20

 

  III-IV

19

 

Radiological

  Nodule size (mm)

21.83 (SD 10.88)

11.22 (SD 7.56)

Nodule location

  Left lower lobe

12

10

  Left upper lobe

12

10

  Right lower lobe

11

11

  Right middle lobe

5

4

  Right upper lobe

17

8

Nodule type (number)

  Nonsolid or ground-glass opacity

17

13

  Perifissural

8

6

  Part-solid

9

7

  Solid

13

10

  Spiculation

10

7

  1. PN pulmonary nodule, SD standard deviation