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Table 4 Previously reported lipid biomarkers in colorectal liver metastasis

From: A new rapid diagnostic system with ambient mass spectrometry and machine learning for colorectal liver metastasis

Author

Year

Sample size

Modality

Name of lipid

Sample type

Up/Down

Remarks

Shimma [28]

2007

1

MALDI-MS

SM (16:0)

Tissue

Up

Diagnostic Factor

Thomas [29]

2013

3

MALDI-MS

PE (38:6), PE (40:4)

Tissue

Up

Diagnostic Factor

Figueiredo [30]

2018

36

MALDI-MS

Sphingolipids

Tissue

Up

Diagnostic Factor

Glycerophospholipid

Prognostic Factor

Present

2020

75

LC-ESI-MS

Mono-unsaturated fatty acid

Tissue

Up

Diagnostic Factor

  1. MALDI-MS matrix-assisted laser desorption/ionization-mass spectrometry, LC-ESI-MS liquid chromatography-electrospray ionization-mass spectrometry, SM sphingomyelin, PE phosphatidylethanolamine