Table 3 Distribution of ALDH2 rs671 genotype and age-adjusted odds ratio for esophageal cancer according to sex, alcohol consumption, and smoking history
Men | Women | |||
|---|---|---|---|---|
Case/Control | OR (95% CI) | Case/Control | OR (95% CI) | |
Current drinker | ||||
GG | 211/1782 | 1 (reference) | 3/896 | 1 (reference) |
GA + AA | 219/421 | 4.39 (3.54–5.46) | 3/101 | 14.45 (2.45–89.48) |
Nondrinker | ||||
GG | 123/556 | 1 (reference) | 10/2786 | 1 (reference) |
GA + AA | 198/718 | 1.25 (0.97–1.61) | 16/1472 | 2.95 (1.35–6.76) |
Ever smoker | ||||
GG | 255/1734 | 1 (reference) | 2/155 | 1 (reference) |
GA + AA | 301/842 | 2.41 (2.00–2.91) | 1/35 | 2.02 (0.09–22.02) |
Never smoker | ||||
GG | 79/604 | 1 (reference) | 11/3527 | 1 (reference) |
GA + AA | 116/297 | 2.95 (2.15–4.07) | 18/1538 | 3.49 (1.67–7.67) |