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Table 11 For genes with at least five hemimethylation sites in both tumor and normal samples

From: Statistical and bioinformatic analysis of hemimethylation patterns in non-small cell lung cancer

Gene name

Count

Family

Gene Description

RGPD5

16

RANBP2 like and GRIP domain containing 5

RGPD8

16

RANBP2 like and GRIP domain containing 8

ROCK1P1

13

Rho associated coiled-coil containing protein kinase 1 pseudogene 1

THAP4

8

THAP domain containing 4

SGTA

8

small glutamine rich tetratricopeptide repeat containing alpha

PTPRN2

7

protein tyrosine phosphatase receptor type N2

CNTNAP3

7

contactin associated protein like 3

NUTM2A-AS1

7

NUTM2A antisense RNA 1

RBFOX3

7

RNA binding fox-1 homolog 3

ESPNP

6

espin pseudogene

FOXK1

6

forkhead box K1

HOXA3

6

HP, TF

homeobox A3

LMF1

6

lipase maturation factor 1

USP45

6

ubiquitin specific peptidase 45

LOC101928782

6

RNA Gene affiliated with the lncRNA class

PRDM16

5

OG, TF, TCG

PR/SET domain 16

RGPD4

5

RANBP2 like and GRIP domain containing 4

MERTK

5

PK

MER proto-oncogene, tyrosine kinase

FAM160A1

5

family with sequence similarity 160 member A1

PRKAR1B

5

protein kinase cAMP-dependent type I regulatory subunit beta

MAD1L1

5

mitotic arrest deficient 1 like 1

HOXA2

5

HP, TF

homeobox A2

DPP6

5

dipeptidyl peptidase like 6

DIP2C

5

disco interacting protein 2 homolog C

FANK1

5

fibronectin type III and ankyrin repeat domains 1

GAL3ST3

5

galactose-3-O-sulfotransferase 3

FLJ12825

5

RNA Gene affiliated with the lncRNA class

KLF5

5

TF

Kruppel like factor 5

ISL2

5

HP, TF

ISL LIM homeobox 2

CBFA2T3

5

OG, TF, TCG

CBFA2/RUNX1 translocation partner 3

SBNO2

5

strawberry notch homolog 2

GIPR

5

gastric inhibitory polypeptide receptor

SCAF1

5

SR-related CTD associated factor 1

COL6A1

5

collagen type VI alpha 1 chain

NEXMIF

5

neurite extension and migration factor

GK5

5

glycerol kinase 5

  1. The gene name, corresponding number of hemimethylated sites (i.e., count), specified gene family, and a description of the gene are formatted in the table’s respective columns. Descriptions are derived from the Molecular Signature Database [14] and the GeneCards database [15]. Certain genes are indicated as members of specific gene families, as shown in the third column: “TF” for transcription factor, “TS” for tumor suppressor, “OG” for oncogene, “HP” for homeodomain protein, “TCG” for translocated cancer gene, and “PK” for protein kinase